-
1. Where do ovarian carcinomas most commonly arise from?
Germinal epithelium
-
2. What are the complications of an ovarian cyst?
Rupture (causing pain), haemorrhage (causing pain and possible shock), torsion (infarction and pain)
-
3. What are the most common ovarian cancers and who do they develop in?
postmenopausal women, from epithelium.
-
4. What is the most common ovarian carcinoma?
Serous cystadenoma (adenocarcinoma)
-
5. What are the 4 types of epithelial tumour?
serous cystadenoma, mucinous cystadenoma, endometrioid carcinoma, clear cell carcinoma.
-
6. What are the 3 types of ovarian primary neoplasm?
epithelial, germ cell, sex cord.
-
7. Which kind of ovarian tumour secretes oestragen?
granulosa cell tumours.
-
8. Which tumours cause Meig's syndrome?
Fibroma (benign)
-
9. What are the commonest ovarian masses in a premenopausal woman?
simple cyst, dermoid cyst (hair, skin etc), endometrioma, benign epithelial tumour
-
10. What are the commonest ovarian masses in a postmenopausal woman?
Benign epithelial tumour, malignancy
-
11. What are risk factors for ovarian cancer?
No. of ovulations: early menarche, late menopause, nulliparous, no pill.
-
12. What genetic risk factors exist for ovarian cancer?
BRCA1 (less so BRC 2)
-
13. Which cancers are most likely to cause ovarian metastasis?
breast and GI.
-
14. Where do you examine?
Breast, pelvis and abdo
-
15. What investigations do you request for ovarian malignancy?
US, Ca125, LFT, chest X ray. Check surgical fitness: FBC, U + E, crossmatch. Risk of malignancy index, then MDT
-
16. how is risk of malignancy calculated?
Ca-125 x pre/post menopausal (1 or 3) x ultrasound findings (0, 1 or 3)
-
17. What are the 2 most important aspects of prognosis?
stage and grade
|
|
