Ovarian malignancy

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  1. 1. Where do ovarian carcinomas most commonly arise from?
    Germinal epithelium
  2. 2. What are the complications of an ovarian cyst?
    Rupture (causing pain), haemorrhage (causing pain and possible shock), torsion (infarction and pain)
  3. 3. What are the most common ovarian cancers and who do they develop in?
    postmenopausal women, from epithelium.
  4. 4. What is the most common ovarian carcinoma?
    Serous cystadenoma (adenocarcinoma)
  5. 5. What are the 4 types of epithelial tumour?
    serous cystadenoma, mucinous cystadenoma, endometrioid carcinoma, clear cell carcinoma.
  6. 6. What are the 3 types of ovarian primary neoplasm?
    epithelial, germ cell, sex cord.
  7. 7. Which kind of ovarian tumour secretes oestragen?
    granulosa cell tumours.
  8. 8. Which tumours cause Meig's syndrome?
    Fibroma (benign)
  9. 9. What are the commonest ovarian masses in a premenopausal woman?
    simple cyst, dermoid cyst (hair, skin etc), endometrioma, benign epithelial tumour
  10. 10. What are the commonest ovarian masses in a postmenopausal woman?
    Benign epithelial tumour, malignancy
  11. 11. What are risk factors for ovarian cancer?
    No. of ovulations: early menarche, late menopause, nulliparous, no pill.
  12. 12. What genetic risk factors exist for ovarian cancer?
    BRCA1 (less so BRC 2)
  13. 13. Which cancers are most likely to cause ovarian metastasis?
    breast and GI.
  14. 14. Where do you examine?
    Breast, pelvis and abdo
  15. 15. What investigations do you request for ovarian malignancy?
    US, Ca125, LFT, chest X ray. Check surgical fitness: FBC, U + E, crossmatch. Risk of malignancy index, then MDT
  16. 16. how is risk of malignancy calculated?
    Ca-125 x pre/post menopausal (1 or 3) x ultrasound findings (0, 1 or 3)
  17. 17. What are the 2 most important aspects of prognosis?
    stage and grade
Card Set
Ovarian malignancy
obs + gynae
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