bio 214 history

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mendel
- law of inheritance
- peas
- assortment/segregation/dominance
miescher
- extract DNA
- white blood cells
- found DNA
extracted DNA from white blood cells
- mischer
- 1869
boveri/sutton
- sea urchin eggs
- chromosomes carry genetic information
- parental gametes
discovered gametes
chromosomes from each parent
- boveri/sutton
- 1902
griffith
- heritable change
- pneumonia in mice
- 1 strand changed the inactive strand
mice with pneumoniae
changed inactive strand

Griffith 1928
beadle/tatum
- 1 gene-1 enzyme/1 polypeptide
- bread mold(neurospora)
- mutated genes,
- found genes produce enzymes
mutated bread mold genes
concluded amino acids made growth happen
- beadle/tatum
- 1941
aver/macleod/mccarthy
- dna vs rna vs protease
- t2r cells
- added aser's
- DNAase didn't grow
- transforming principle
transforming principle
DNAase=no growth

Avery/macleod/mccarthy
hersey/chase
- DNA is the changing factor
- e coli/t2
- radioactive material
- DNA in e coli
DNA is the changing factor
radioactive material

hersey/chase
chargaff
- equal nucleotides on each side
- breaking down different species DNA
equal nucleotides
diff species DNA

chargaff
franklin
- xray data
- helix shape
xray data
helix shape

franklin
Watson/crick
- base pairing rules
- figured out DNA structure
figured out DNA structure
base pairing rules

Watson/crick
meselson/stahl
- dna structure confirmed
- sem v. dispersive v. conservative
- bacteria w/N15 & 14
- 1 gen=middle density
- 2nd gen=more 14
N14/15 density over generations
semiconservative

meselson & stahl

Author

lacythecoolest

273541

Card Set

bio 214 history

Description

DNA history

Updated

2014-05-07T02:58:07Z

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