molecular genetics

what is cystic fibrosis

a mutation in the CFTR gene that is due to a three base pair deletion
CF is characterized by

accumulationn of sticky mucus in the lungs and digestive system
what does the mutation cause the CFTR gene to do

encodes a non-functioning ion channel protein
2 vectors that can be utilized in gene therapy for gene delivery
- viral vectors
- nonviral vectors
4 gene therapy challeneges
- gene delivery and activation
- triggering an immune response
- disrupting important genes
- cost for development
2 problems with gene delivery and activation in gene therapy
- targeting the correct cell
- allow for activation of inserted gene

Author

kaitiek09

272902

Card Set

molecular genetics

Description

molecular genetics final exam

Updated

2014-05-03T01:33:52Z