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Treats hyperthyroidism by destroying thyroid cells => reduces size of thyroid gland => reduces thyroid hormone production; (oral administration)
Radioactive Iodine (I 131)
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Treats hyperthyroidism (from Graves, Thyroid Storm) by inhibiting thyroid hormone synthesis.
propylthiouracil (PTU)
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Treats hypothyroidism - synthetic T4 that is converted by enzymes to T3; highly protein bound
levothuyroxine [Synthroid]
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Tx of type II diabetes:
_|_ gluconeogenesis in liver, ↑ glucose uptake by muscle; best for use in obese patients
metformin
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Treatment of type II diabetes; ↑ insulin sensitivity of target cells, ↑ glucose uptake by muscle, _|_ gluconeogenesis by liver
rosiglitazone (a thiazoliddinedione/glitazone)
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Side effects of rosiglitazone
Water retention => weight gain, edema, heart failure (can exacerbate sx of existion heart diseas)
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Synthetic T3 thyroid hormone, treatment for hypothyroidism
liothyronine
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Rapid-acting (0.25-.5 hrs), short-duration (3-6 hrs) insulin; Peak effect at 0.25 - 2.5 hrs) good for use after meals; Treatment of type I and type II diabetes
lispro insulin [Humalog]
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Rapid-acting (0.5 hr), short-duration (4-12 hrs) insulin. Peak effect at 2.5-5 hrs; Can be administered via IV and IM
regular insulin [Humulin R, Novolin R]
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Long-acting (onset 3-4 hrs), long-duration (>=24 hrs) insulin; no peak effect; should not be mixed with other insulins;
insulin glargine [Lantus]
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Intermediate-acting (onset 1-2 hrs), intermediate-duration (14-24 hrs) insulin; peak effect at 4-12 hrs; Cloudy suspension; often combined with regular insulin
Neutral Protamine Hagedorn (NPH) insulin [Humulin N, Novolin N]
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Oral hypoglycemic which stimulates release of insulin from pancreas; best for use in leaner (not obese) patients
tolbutamide (a sulfonylurea)
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