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Previously called Pasteurella Pestis
Yersinia Pestis
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Which of the following is a member of the family enterobacteriaceae?
B. Yersinia Pestis
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Which of the following was the cause of the Plague?
C. Yersinia Pestis
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Which of the following is zoonotic?
C. Yersinia Pestis
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True or False:
The plague is only seen today in isolated human incidences.
FALSE- the disease is still seen but mostly in wild animals (prairie dog)
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True or False:
Yersina Pestis is a gram negative rod.
True
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True or False:
Yersinia Pestis is not capsulated.
False- capsulated
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True or False:
The last breakout of Yersinia Pestis was in 1924 in San Francisco.
False- LA area, killed 125,000
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Which of the following has killed more people than any other organism?
E. Yersinia Pestis
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Which of the following drugs is used to treat the bubonic plague? (choose 2)
- B. Streptomycin
- E. Tetracyclin
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This form of the plaque has almost 100% mortality.
A. Pneumonic
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True or False:
Bubonic form of the plague is born by the circulatory system.
False- septicemic
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Which of the following form of the plague causes the most hemorrhages and necrosis in all parts of the body?
B. Septicemic
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When bubonic plague is not properly treated it becomes
C. Septicemic
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When septicemic plague is not properly treated it becomes
D. Pneumonic
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When pneumonic plague is not properly treated it becomes
D. likely that the individual will die
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Which form of the plague has killed more individuals than any other disease?
B. Pneumonic
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True or False:
Pneumonic Plague travels by droplet (air borne) route.
True
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Which of the following is a diagnostic test for Yersinia Pestis?
E. Fluorscent Antibody Test
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Which of the following is not responsible for the pathogenicity of Yersina Pestis?
E. Lysogenized Phage
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The Murein Toxin is associated with which of the following organisms?
B. Yersinia Pestis
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True or False:
Toxin B of the murein toxin is twice the size of Toxin A.
False
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True or False:
Toxin A of the Murein toxin is twice the size of Toxin B.
True
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Which aspect of Yersinia Pestis' pathogenicity makes it able to survive in macrophages?
C. Fibrolytic Toxin
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True or False:
Sulfas are used to treat Yersinia Pestis.
False
-
The Haffkine Vaccin is used to treat what disease?
E. Yersinia Pestis
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True or False:
Primary Pneumonic plague develops from a bubo.
False- Secondary Pneumonic plague
-
True or False:
Primary Pneumonic Plague doesn't go through bubo & septicemic plague phases.
True
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True or False:
Primary Pneumonic Plague is transmitted by droplet route person to person.
True
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True or False:
Diptheria is now one of the most feared diseases.
False- it was one of the most feared diseases in the past.
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Which of the following is a gram positive, club shaped, palisading bacteria?
A. Corynebacterium Diphtheriae
B. Mycobacterium Leprae
C. Yersinia Pestis
D. Clostridium Tetani
E. Mysobacterium Tuberculosis
A. Corynebacterium Diphtheriae
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Which of the following contains metachromatic granules?
D. Corynebacterium Diphtheriae
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Which of the following grows on tellurite media?
B. Corynebacterium Diphtheriae
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How does Corynebacterium Diptheriae grow on media?
C. Black shiny colonies
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Which of the following has a lysogenized phage?
E. Corynebacterium Diphtheriae
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Which of the following determines the pathogenicity of C. Diphtheriae?
D. Lysogenized Phage
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Which of the following is found in the URT, Urinary Tract, skin, etc?
E. Corynebacterium Diphtheriae
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True or False:
C. Diphtheriae infection begins 1-2 weeks after acquired.
False- 2-4 Days (rapidly progressing)
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A 'pseudomembrane' is formed with an infection by which organism?
C. Corynebacterium Diphtheriae
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Where is the psuedomembrane of C. diphtheriae found?
C. Upper respiratory tract
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True or False:
The pseudomembrane formed with a C. diphtheriae infection can block the airway and cause suffocation.
True
-
True or False:
There is a toxin that is produced with an infection by C. diphtheriae.
True- can cause damage to heart, kidneys, & CNS
-
The use of an antitoxin to treat an infection is called
B. Artificial Passive Immunity
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True or False:
Antibiotic therapy is primary in the treatment of C. diphtheriae.
False- Secondary to Artificial Passive therapy
-
Which antibiotics are used to treat C. diphtheriae? (Choose 2)
- A. Clindamycin
- C. Erythromycin
-
Van Behring developed a treatment for which organism?
A. Corynebacterium Diphtheriae
-
True or False:
The DTP vaccine gives lifelong immunity to a patient against Dipththeriae.
True
-
What test is used to determine immunity status to C. diphtheriae?
A. Schick Test
-
Klebs-Loefler Bacilli
C. Corynebacterium Diphtheriae
-
Granules can be stained with methylene blue
C. Corynebacterium Diphtheriae
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True or False:
The endotoxin of C. Diphtheriae is made up of two components linked by a disulfide bond.
False- EXOTOXIN
-
No inflammation during the Schick test indicates:
A. That the person is immune to C. diphtheriae
-
Inflammation on the toxin side after the Schick test indicates that
B. That the person has no immunity to C. diphtheriae
-
Inflammation on the Antitoxin side after the Schick test indicates that
B. That the person is hyperimmune to C. diphtheriae
-
True or False:
Corynebacterium is associated with the eyes.
True
-
True or False:
Tellurite Media is composed of a salt agar and Te2O3.
False- Blood agar + Te2O3
-
True or False:
C. Diphtheriae & C. xerosis are NOT hemolytic.
False
-
True or False:
C. Diptheriae does nitrate reduction.
True
-
True or False:
Legionnaires disease was discovered in 1965 at the Bellvue Stratford Hotel.
False- 1976
-
True or False:
Legionella pneumophila is a gram negative rod
True
-
Which organism is associate with AC units?
E. Legionella Pneumophila
-
What was used to culture Legionella pneumophila?
C. Chicken eggs
-
Pontiac Fever is associated with which organism?
C. Legionella Pneumophila
-
True or False:
Legionella is difficult to grow because it requires high iron and sulfates.
False- iron & pyrophosphate
-
True or False:
The pathogenicity of Legionella is its lysogenized phage.
False- Lipopolyscaccaride protein complex
-
True or False:
Pontiac Fever is more deadly than Legionella.
False
-
True or False:
Erythromycin and Ethambutol are used to treat Legionella.
False- erythromycin & rifampin
-
True or False:
Acid Fast staining is used for Corynebacterium.
False- Mycobacterium
-
Which of the following are unique characteristics to Mycobacterium cell walls?
C. All of the above
-
Which of the following is impervious to chemicals? (2)
- E. Mycobacterium Leprae
- E. Mysobacterium Tuberculosis
-
True or False:
Mycobacterium has teichoic acid in the cell wall like gram negative bacteria.
False- lacks teichoic acid
-
True or False:
The cheapest test for tuberculosis is the tuberculin test.
False- Ziehl Neelsen
-
Which of the following are TB tests? (choose 2)
A. Fluorscent Antibody Test
B. Acid Fast Staining
C. Ziehl Neelsen Test
D. Schick Test
E. PCR
- B. Acid Fast Staining
- C. Ziehl Neelsen Test
-
Phthesis & Consumption are other names for an infection from
A. Mysobacterium Tuberculosis
-
An infection of this causes allergic granulomas to form.
A. Mysobacterium Tuberculosis
-
True or False:
Tubercles have a caseous appearance on X-Ray
True
-
True or False:
TB of the brain causes fusion of the vertebrae.
False- TB of the spinal cord
-
True or False:
Miliary TB affects the lungs.
False- Pulmonary TB
-
True or False:
Miliary TB forms tubercles at sites such as liver, spleen, and kidney.
True
-
True or False:
TB is a major problem for AIDS victims today
True
-
True or False:
TB is genetic.
False
-
True or False:
Mycobacteria survive in macrophages better than any other organism.
True
-
The tuberculin test uses what to scan a population for exposure?
D. Purified Protein Derivate
-
Which of the following tests would not be helpful in determining a TB diagnosis?
D. Schick Test
-
True or False:
The tuberculin test is more sophisticated than the Mantoux test for TB.
False
-
TB is identified by the presence of:
E. Trahalose
-
Cord Factor is associated with which organism?
A. Mysobacterium Tuberculosis
-
What kind of media is TB grown on?
D. Glycerol rich
-
Waksman developed the first drug used to treat what?
A. Mysobacterium Tuberculosis
-
What was the first drug used to treat TB?
B. Streptomycin
-
What is the first line combination therapy now used to treat TB?
B. Ethambutol + INH
-
What year was Streptomycin developed as an anti-tuberculous drug?
B. 1945
-
True or False:
A tubercle is another name for a ragged cavity.
False- granuloma
-
Sanatoriums are associated with a disease caused by which organism?
E. Mysobacterium Tuberculosis
-
True or False:
BCG vaccine is routinely used in the US.
False- routine in many other countries
-
BCG vaccine is used to prevent an infection from which organism?
C. Mysobacterium Tuberculosis
-
Which of the following organisms are NOT known for producing TB or a TB-like disease?
C. M. fortuitum
-
True or False:
Mycobacterium is resistant to penicillin.
True
-
True or False:
Corynebacterium is resistant to penicillin.
False
-
Hansen's Disease is another name for a disease caused by which organism?
A. Mycobacterium Leprae
-
What is the only known exception to Koch's postulates?
C. Mycobacterium Leprae
-
Which of Koch's Postulates does M. Leprae NOT follow?
B. Must be isolated from a diseased organism and grown in pure culture.
-
Armadillos are associated with which disease?
E. Mysobacterium Tuberculosis
-
In what organism does M. Leprae grow most abundantly?
E. Humans
-
True or False:
The incubation time for M. Leprae is very short.
False- long (years to decades)
-
True or False:
M. Leprae has a long division cycle.
True (12 days)
-
How many forms of Leprosy are there?
B. 2
-
Which form of Leprosy shows granulomas that are large and disfiguring?
A. Tuberculoid
B. Lepromatous
B. Lepromatous
-
True or False:
Another name for the lepromatous form of leprosy is anesthetic.
False- tuberculoid form= anestetic
-
In which form of leprosy does the victim lose pigment & sensation?
A. Tuberculoid
B. Lepromatous
A. Tuberculoid
-
What is the only organism that destroys peripheral tissue, skin, and mucous membranes?
E. Mycobacterium Leprae
-
True or False:
M. Leprae has predilection for colder parts of the body.
True
-
True or False:
M. Leprae has predilection for warmer parts of the body.
False- colder
-
The Lazar house is associated with the disease caused by which organism?
C. Mycobacterium Leprae
-
Which of the following is not a test used to diagnose Leprosy?
C. Schick Test
-
True or False:
A positive Lepromin test means that the patient has leprosy.
False- just exposed
-
Which of the following is not used to treat leprosy?
C. Erythromycin
-
True or False:
Leprosy is curable.
False- must always take drugs
-
ENL is associated with which organism?
D. Mycobacterium Leprae
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