*Pharmacology*

Sudden, life-threatening lung failure in which the alveoli inflame, fill with liquid and collapse, ceasing gas exchange & starving body of oxygen. Requires treatment with mechanical ventilation.

The resistance to ventilation caused by movement of gas through airway

indicates the STRUCTURE of the drug

Group of progressive diseases that cause airflow blockage, and breathing-related problems. (Ex: chronic bronchitis, emphysema, asthma)

name assigned by MANUFACTURER to a chemical that shows potential as a drug

is an inherited disease of your secretory glands, that causes thick, sticky mucus to build up in the lungs and digestive tract.

reflects the drug's chemical name but in shorter form.

name of drug used in U.S. Pharmacopeia

any chemical that alters body and/or mind without any nutritional value

study of drugs, their origins, properties, and effects

the preparation and dispensing of drugs

identifying sources of drugs from plants & animals

studies the relationship between genetics & drug effects

non-trademarked name

art of treating disease with drugs

study of toxic substances and their actions (Ex. antidote, poison control)

drugs made from this are used to treat Arrhymias and CHF

find new chemical with potential for useful physiological effects

examines general effects on animal & specific organs; toxicology examines mutations & effects on fertility

application filed with the FDA including all info on chemical and plans for human studies

• 3 Phases of Human Studies
• i. small # of healthy subjects
• ii. small # of subjects with the disease
• iii. large, multicenter studies

filed with FDA after successful IND. once approved, drug is released for general use and may be prescribed for treatment.

intravenous administration for acetaminophen overdose

prevention/treatment of Respiratory Distress Syndrome (RDS) in newborns

treatment of cystic fibrosis, increase in airway secretion clearance

treatment of persistent pulmonary hypertension in newborns & acute respiratory distress in adults

drug for the diagnosis or treatment of a rare disease

written order for a drug, including instructions for dispensing & taking the drug

• 1. patient's name, address, & date
• 2. "Rx" (recipe/take thou) - superscription tells pharmacist to take drug listed and prepare medication
• 3. inscription lists names and quantity of drug being prescribed
• 4. subscription directions for how to prepare the medication
• 5. transcription or signature info on patient's med. label (instructions)
• 6. name of prescriber physician's name

available to the general population without a prescription

• (B-Adrenergic) for relaxation of bronchial smooth muscle & bronchodilation, to improve flow in airway obstruction caused by COPD or asthma
• [Albuterol, (Ar)Formoterol, Isoetherine, Levalbuterol, Metaproterenol, Pirbuterol, Salmeterol]

(A-Adrenergic) for relaxation of induced bronchoconstriction, to improve flow rates in COPD or asthma patients

[Epinephrine, Ipotropium bromide, Tiotropium bromide]

mimics properties of mucus; lowers resistance and promotes clearance of secretions

[Acetylcysteine, Dornase alfa]

to reduce and control airway inflammatory response

[Budesonide, Ciclesonide, Flunisolide]

prevents the onset & development of the asthmatic response

[Cromolyn sodium, Zafirlukast, Nedocromil sodium, Montelukast]