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Procainamide (Pronestyl) Class
Antiarrythmic
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Procainamide (Pronestyl) Actions
Suppresses phase 4 depolarization in normal ventricular muscle and purkinje fibers reducing the automaticity of ectopic pacemakers
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Procainamide (Pronestyl) Indications
- 1. Second line for atrial and ventricular arrhythmias
- 2. Recurrent VF / VT
- 3. wide complex tachycarida
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Procainamide (Pronestyl) Contraindications
- 1. Do not use in AV block or bradycardia
- 2. Digitalis Toxicity
- 3. Preexisting QT prolongation
- 4. Torsades de Pointes
- 5. TCA Toxicity
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Procainamide (Pronestyl) Precautions
caution in patient's with MI and renal / hepatic disfunction
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Procainamide (Pronestyl) Side Effects
- 1. Hypotension, AV block, wide QRS, bradycardia, asystole
- 2. CNS depression, hallucination, confusion, dizziness, siezures
- 3. nausea vomitting, fever
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Procainamide (Pronestyl) Dosage
VT / VF refractory to lidocaine: 100mg over 5 minutes or 20 mg / min
- End point of medication is reached if:
- 1. suppression of arrhythmias
- 2. 17 mg / kg reached
- 3. QRS wider than 50%
- 4. Hypotension
Infuse at 1 mg / min if med suppresses VT. Reduce in renal failure
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Procainamide (Pronestyl) Route
IV infusion
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Procainamide (Pronestyl) How supplied
vial: 1gm / 10ml or 1gm / 2ml
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Procainamide (Pronestyl) Pediatrics
Not recommended
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