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Motor Tracings
Frontal Lobe -> Internal Capsule -> Mesencephalon -> Pons -> Medulla -> Ventral Horn -> Ventral Root -> Ramus -> Plexus -> Nerve(s) -> Muscle
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Sensory Tracings
Receptor -> Nerve(s) -> Plexus -> Ramus -> Dorsal Root Ganglion -> Dorsal Root -> Dorsal Horn -> Thalamus -> Internal Capsule -> Parietal Lobe
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Cranial Nerves
- 1. Olfactory: Smell
- 2. Optic: Vision
- 3. Oculomotor: Motor
- 4. Trochlear: Motor
- 5. Trigeminal: Opthalmic
- 6. Abducens: Motor
- 7. Facial: Motor and Acoustic
- 8. Vestibulocochlear: Learning
- 9. Glossopharyngeal: Tongue
- 10. Vagus: Mixed Autonomic
- 11. Accesory: Swallowing
- 12. Hypoglossal: Tongue
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Functions of the Blood Brain Barrier
- Plexus at 3rd and 4th ventricles (capillary beds)
- Prevents passage of unwanted material
- Actively transports glucose to the brain
- Increases permeability of hypothalamus and pineal gland
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Functions of Cerebrospinal Fluid
- Cushion delicate structures
- Float brain
- Provides nutrients and hormones, and removes wastes
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Reflex Arc
- 1. Stimulus
- 2. Sensory information sent to Central Nervous System
- 3. Processing and coordination of information
- 4. Motor command sent
- 5. Response by effector
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Classification of Reflexes
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Protection
- Spinal CordVertebrae
- Meninges
- Cerebrospinal fluid
- BrainSkull
- Meninges
- Cerebrospinal fluid
- Blood brain barrier
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Circulation of Cerebrospinal Fluid
- Produced at choroid plexus at each ventricle
- Goes from lateral ventricle -> intraventricular foramen -> 3rd ventricle -> cerebral aqueduct -> 4th ventricle
- Goes to subarachnoid space where it travels through brain and spinal cord
- Enters spinal cord and gets reabsorbed at arachnoid granulations
- Enters superior sagittal sinus
- Enters blood system
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Effects of sympathetic stimulation
- Increased alertness
- Feeling of energy and euphoria
- Excites cardiovascular and respiratory centers
- Increase muscle tone
- Release of glycogen and lipids = energy
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General functions of the parasympathetic nervous system
- Constriction of pupils
- Secretion by digestive glands
- Secretion if hormones
- Increased smooth muscle activity
- Constriction of respirstory passageways
- Reduction in heart rate and force of contraction
- Sexual arousal
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Relationship between sympathetic and parasympathetic nervous systems
- Dual innervation
- Cranial area regions reached by chain ganglia and cranial ganglia
- Thoracic and abdominal regions innervated by plexuses
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Higher order functions
- Performed by cerebral cortex
- Involve conscious and unconscious control
- Involve complex interactions between brain areasa
- Are subject to learning and modification through time
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Reticular activating system
- Gradations of consciousness
- Interactions of many brain areas
- Primary function is to keep you awake and alert
- Poorly defined network projects onto cerebral cortex
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Orders of Neurons
- 1st Order Neuron: Dorsal Root -> Spinal Cord
- 2nd Order Neuron: Spinal Cord -> Thalamus / Cerebellum
- 3rd Order Neuron: Thalamus -> Cerebral Cortex
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Conscious States of Reticular Activating System
- Delirium
- Dementia
- Confusion
- Normal consciousness
- Somnolence
- Chronic vegetative state
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Unconscious States of the Reticular Activating System
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Somatic and Autonomic Pathways
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Sympathetic vs. Parasympathetic
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Preganglionic Neuron
- Myelinated
- Usually produced Ach
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Postganglionic Neuron
- Unmyelinated
- Releases Ach or NE as needed
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Sympathetic Ganglionic Neurons
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Sympathetic Synapses and Receptors
- 2 Types of Synapses
1. Cholinergic: releases Ach between preganglionic neuron and ganglion - 2. Adrenergic: between postganglionic and receptor (Ach and/or NE)
- 2 Types of Receptors1. Adrenergic
- - alpha: Smooth muscle and sphincter, blood vessels
- - beta: Skeletal, smooth, increased metabolic rate
- 2. Cholenergic: Respond to Ach, effect sweat glands, general relaxation
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Parasympathetic Signals and Receptors
- -All neurons respond to Ach
- 2 Types of Receptors
1. Nicotrinic: Respond to Ach in excitatory manner - "preganglionic"
- 2. Muscarinic: Found in neural effector junction
- Excitatory
- Inhibitory
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Effects of Sympathetic Stimulation
- Increased Alertness
- Feeling of energy and euphoria
- Excites cardiovascular and respiratory centers
- Increased muscle tone
- Release of glycogen and lipids = energy
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General Senses
- Temperature
- Pain
- Touch
- Pressure
- Vibration
- Proprioception
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Special Senses
- Smell
- Taste
- Balance
- Hearing
- Vision
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Receptors
- Each receptor has characteristic sensitivity
- - Receptor specificity
- - Receptor Field: Area monitored by a single receptor cell
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Adaptation
- Peripheral (sensory) Adaptation: Receptors or sensory neurons alter their levels of activity
- Synaptic Fatigue:
- - Phasic receptors: Fast-adapting receptors
- - Tonic receptors: Slow-adapting receptors
- Central Adaptation: inhibition of nuclei
- - Restricts the amount of detail arriving at the cerebral cortex
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Receptors General Senses
- Exteroceptors provide information about the external environment
- Proprioceptor monitors body position
- Interoceptors monitor conditions inside the body
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Receptors for Special Senses
- Nociceptors respond to tissue damage
- Thermoreceptors respond to change in temperature
- Mechanoreceptors are stimulated by physical distortion, contact, or pressure
- Chemoreceptors monitor the chemical composition of body fluids.
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Main Functions of Digestive System
- Ingestion
- Mechanical Processing
- Digestion
- Secretion
- Absorption
- Excretion
- Compaction
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Pancreas
Exocrine cells secrete buffers and digestive enzymes; endocrine cells secrete hormones
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Mesenteries
- 1. Falciform Ligament: Diaphragm to liver
- 2. Greater Omentum: Greater curvature of stomach, wraps around small intestine goes back and attached to large intestine and posterior wall
- 3. Lesser Omentum: Lesser curvature of stomach to liver and posterior wall
- 4. Mesocolon: Large intestine to posterior wall
- 5. Mesentary Proper: Small intestine to posterior wall
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Functions of Mesentary
- Support organs, veins, arteries, lymphatic, adipose, connective tissue
- Provides nutrients, O2, collects waste, collects bacteria
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Swallowing
- Buccal Phase: Compress bolus against hard palate, elevates soft palate, tongue retracts
- Pharyngeal Phase: Bolus touches posterior pharyngeal wall, epiglottis tips backwards, bolus enters esophagus
- Esophageal Phase: Upper esophageal sphincter opens, peristalsis begins, lower esophageal sphincter opens
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Histology of Digestive System
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Cerebrum
- Conscious thought, memory, and learning
- Frontal Lobe: Primary Motor Cortex
- Occipital Lobe: Primary Visual Cortex
- Parietal Lobe: Primary Sensory Cortex
- Temporal Lobe: Primary Auditory and Olfactory Cortex
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Basal Ganglia Nuclei
- Controls large subconscious movements
- Involved in starting, stopping, and intensity of movement
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Thalamus
- Sensory "relay station" for cerebral cortex
- Primitive awareness of sensory information
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Hypothalamus
- Main control center for ANS
- Center of emotion (rage, fear, pleasure, libido)
- Sleep-wake cycles
- Endocrine control
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Cerebral Peduncle
Contain "pyramidal" tracts descending from cortex towards spinal cord
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Corpora Quadrigemina
- Involved in visual reflexes (tracking of eyes on a moving target)
- Involved in auditory reflexes ("startle reflex" to loud sound)
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Pons
- Bridge between cerebral cortex and cerebellum for coordination of voluntary movement
- Smooths transition between inhalation and exhalation
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Cerebellum
- Receives information about equilibrium, movement of body, motor commands from cerebral cortex
- Smooths and coordinates body movements
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Medulla Oblongata
- Pathway for sensory relay
- Visceral centers for autonomic function
- Works with hypothalamus
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