F40 AVAMYS

It is a nasal hypersensitivity symptoms induced by an immunologically mediated inflammation after the exposure of the nasal mucous membranes to an offending allergen.
 

Any antigen that interacts with the body’s immune system to give rise to allergic response.

It is condition where the body recognizes a substance as non-self and is considered a threat thus stimulating the immune system to react and manufacture chemicals to “eradicate” the intruder.

Based on the 2008 National Nutrition and Health Survey, the prevalence of allergic rhinitis is

Asthma and allergic rhinitis occur in a continuous airway, two diseases frequently co-exist. Guidelines and studies estimate that about ___ of AR patients have asthma and __ of asthma patients have allergic rhinitis

A study by Nolte et al conducted to 726 participants showed that Rhinitis was undiagnosed in __% of patients and __% with moderate to severe rhinitis were undertreated.

It has been suggested that the association of allergic rhinitis with other inflammatory diseases may be the result of the commonly shared airways in all these disorders. What are the complications of AR?

People with allergic rhinitis (AR) rate their overall  health significantly lower than individuals without nasal allergies. Compared with the general population, more people with AR complain with?

Cells initiating the allergic response.

Trademark of the allergic inflammation

The initial exposure of your body to the allergen

Early phase of allergic process happens in:

Late phase of allergic process happens

The cardinal symptoms of allergic rhinitis are the ff:

It involves symptoms that are significantly worse during “pollen season”, usually during the summer months   usually caused by common seasonal allergens or outdoor allergens such as grass and tree pollen and weeds.

The allergic rhinitis with symptoms that are continuous or intermittent throughout the year
It is usually caused by indoor allergens such as dust mites, tobacco smoke and pet dander 

4 days per week or < 4 weeks

> 4 days per week and > 4 weeks

What is the primary treatment goal for patients with allergic rhinitis

The prevalence of Allergic Rhinitis in the Philippines

Other symptoms of AR

What are the manifestation of a px with ocular symptoms?

What is the most bothersome symptom of AR that was ranked by affected individuals?

Based on studies, % of px with AR suffer from ocular symptoms.

According to ARIA, a px experiencing normal sleep, no impairment of daily activities, normal work and no troublesome symptoms considered as

According to ARIA, a px experiencing abnormal sleep, impairment of daily activities, abnormal work and troublesome symptoms considered as

What is the 1st line therapy in individuals with mild symptoms?

What is the most effective tx for AR?

The H1 receptor antagonists

It is the most effective tx option for preventing and alleviating the symptoms of AR, may have variable efficacy in terms of relieving symptoms.

It is classed as mast cell stabilizers used in many countries as eye drops and show limited efficacy for the nasal symptoms of AR.

It induce vasoconstriction to reduce nasal congestion but show little effect against other nasal symptoms and show rapid onset of action.

It bind to receptors on the glandular tissue to decrease the duration and severity of watery rhinorrhea.

An agent that block leukotriene receptors to inhibit the release of inflammatory cells and prevent nasal swelling.

A controlled procedure that exposes the affected AR sufferer to known allergens to reduce symptom severity.

Avamys is a nasal spray in white, uniform suspension contained in an amber glass bottle, fitted with a metering (___ microliters) atomising spray pump.

Each spray of the suspension delivers approximately ___ micrograms of micronised Fluticasone furoate as an ex-device dose.

What is the plasma protein binding of Avamys?

The absolute bioavailability of Avamys administered as 880 mcg 3x per day is.

Elimination of Avamys was primarily via ____ route following oral and intravenous indicative of excretion of FF and its metabolites via the bile.

What is the dosing for adult and adolescence with SAR?

What is the dosing of children with SAR?

Tx of the nasal symptoms and ocular symptoms of SAR is indicated to.

Tx of nasal symptoms of SAR and PAR is indicated to

What is the on set of action of Avamys?

The recommended starting dosage in adults and adolescents

The recommended daily dose for children

Avamys is contra indicated in which type of px

According to Meltzer, how many of adult patients want fast relief of symptoms

6 out of 10 patients want relief of AR symptoms within an average of: 

How much percentage will be reduced on Nasal Symptoms given the Avamys 110mcg once daily in SAR vs placebo?

How much percentage will be reduced on ocular symptoms given the Avamys 110mcg daily in SAR vs placebo

Acccording to Salter, Avamys is safe and well-tolerated to use for how long?

how much is the daily treatment cost of Avamys given with the coupons?