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Endocrine system
The collection of cells glands and tissues of an organism that secretes hormones directly into the bloodstream.
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Hormones
A class of regulatory biochemicals produced in particular parts of organisms by specific cells then transported by the bloodstream to other parts of the body
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Endocrinology
Branch of biology and medicine dealing with the endocrine system.
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Endocrine glands
Glands of the endocrine system that secrete their products, hormones, into the blood rather than though a duct.the main are pituitary, thyroid, adrenal, pancreas,ect.
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Exocrine glands
Sweat glands, salivary, liver excretes it's essential product by way of a duct.
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Receptors
molecule usually found inside or on the surface of a cell that receives chemical signals from outside the cell.
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lipid soluble hormones
steroid derived from cholesterol
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water soluble hormones
Amin synthesized by modifying certain amino acids
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target cells
a cell that has receptors for signaling molecule like a hormone or drug or focus for contact via virus phagocyte nerve ending etc.
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function of hormones
to maintain a function and respond to certain changes in the bodies environment
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first messenger
hormone that binds to an exterior receptor on a cell to initiate intracellular activity
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second messenger
substance that is released in the reaction to a hormone and brings about a response by the cell
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Cyclic AMP
Cyclic mononucleotide of adenosine formed from ATP and is responsible for intercellular mediation of hormonal effects on cells
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transport proteins
- 1) make lipid soluble hormones water-soluble temporarily
- 2) slow the passage of small hormone molecules to the filtering mechanism in the kidneys slowing the rate of hormone loss through urine
- 3) provide a Ready Reserve of hormone already present in the bloodstream
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mechanism of action of lipid soluble hormones
- 1) lipid soluble hormones detaches from the transport protein in the blood stream the diffuses through the interstitial fluid and into the lipid bilayer of a cell
- 2) if the cell is a Target cell the hormone binds to and activates receptors located within the nucleus and the activated receptor hormone complex alters gene expression by turning specific genes on or off
- 3) as DNA is transcribed mRNA is formed and leaves the nucleus to direct the synthesis of a new protein on the enzymes
- 4) new protein alters the cell's activities caused in their response typical of the original hormone
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mechanism of action of water soluble proteins
- 1) water soluble hormones the fuses through interstitial fluid and binds to the exterior receptor cells plasma membrane as the first messenger
- 2) because of The Binding ATP is converted into cAMP inside the side of cytosol
- 3) cAMP acting as the second messenger activate several enzymes
- 4) activated enzymes catalyze reactions producing physiological responses
- 5) after cAMP is deactivated the cells response
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permissiveness
allowing a biological /biochemical process to occur
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synergism
interactions of drug hormones such that the total of fact is greater than the sum of the individual effects
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antagonism
interaction of drug hormones such that the total effect is less than the sum of the individual effects
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feedback loops
- 1) negative resists a change in the body system
- 2) positive increases the amount of a change in the body
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regulation of hormone secretion
blood levels are controlled by negative feedback synthesized and released in response to humoral stimuli, neural stimuli, and hormonal stimuli
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hypothalamus
region of 4 brain below thalumus coordinates ANS and the activity of the pituitary controlling body temperature thirst hunger and other homeostatic systems it is also involved in sleep and emotional activity
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pituitary gland
ti si body attach to the base of the brain is the major endocrine gland important in controlling growth development and the functioning of other endocrine Systems
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Infundibulum
passage connecting the middle sinus meatus with anterior ethmodial cells and the frontal sinus
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posterior pituitary
composed of the infundibulum and neural lobe secretes various hormones
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oxytocin
hormones secreted by the pituitary gland that most often stimulates contractions of the uterus during childbirth
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anti diuretic hormone (ADH)
hormone that promotes retention of water by the kidneys and increases blood pressure
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anterior pituitary
interior part of the pituitary gland derived from the pharynx and is glandular in nature
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Hypophyseal portal system
connects the hypothalamus and the anterior lobe of the pituitary gland and acts as a route for releasing and inhibiting hormones
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growth hormone
peptide hormone that stimulates growth reproduction and regeneration
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prolactin (PRL)
hormone released from the anterior pituitary that stimulates milk production
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tropic hormones
hormones that have other endocrine glands as their target mostly produced in secreted by the anterior pituitary
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releasing hormones
hormone produced by the hypothalamus that accelerates secretion of a given hormone
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inhibiting hormones
that inhibits the secretion of hormones
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Thyroid stimulating hormone (TSH)
hormone secreted by the pituitary gland that regulates production of thyroid hormones
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Adrenocorticotropic hormone(ACTH)
hormone secreted by the pituitary gland that stimulates the adrenal cortex
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follicle stimulating hormone(FSH)
hormone secreted by the anterior pituitary that promotes the formation of ova or sperm
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lutenizing hormone(LH)
hormone secreted by the anterior pituitary that stimulates ovulation in females and synthesis of the androgen in males
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melanocyte stimulating hormone(MSH)
hormone secreted by pituitary gland involved and changes and pigmentation
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insulin like growth factors (IGF`S)
one of two polypeptides similar in structure to insulin secreted during fetal development or childhood and mediate growth hormone
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growth hormone-releasing hormone(GHRH)
releasing factor that accelerates secretion of growth hormone by the Pituitary gland
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growth hormone inhibiting hormone(GHIH)
hormone secretion of growth hormone by the anterior pituitary gland
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thyroid gland
large ductless glands in the neck that secretes hormones regulating growth and development through the rate of metabolism
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follicles
small secretory cavity or gland
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Colloid
a substance made up of a single substance dispersed throughout another substance
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Thyroid hormone
hormone produced by the thyroid increases increases ATP production accelerates body growth enhances cholesterol secretion contribute to the development of nervous systems
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T4
more of it released than T3
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formation and storage of thyroid hormone
created when iodine is attached to tyrosine and stored in the thyroid until blood levels get low enough to require it
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calcitonin
hormone secreted by the thyroid that lowers blood pressure
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parafollicular cells(Ccells)
neuroendocrine cells in the thyroid with the primary function of secreting calcitonin
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the parathyroid gland
I'm all endocrine glands above or inside thyroid that produce parathyroid hormone
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Oxyphil cells
cell in the parathyroid gland that has no apparent use
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chief cells
produces parathyroid hormone
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parathyroid hormone(PTH)
regulates calcium levels in a person's body
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the adrenal glands
the small gland on top of the kidney producing hormones that help control heart rate blood pressure and how the body uses food mineral levels in the blood and other functions it's also used in stress reactions
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medulla
secretes epinephrine and nonepinephrine
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corticosteroids
Android hormone produced in the adrenal cortex having various metabolic functions
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Zona glomerulosa
outermost layer of the adrenal cortex made of glandular epithelial cells (salt)
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Zona fasciculata
middle layer of the adrenal cortex made of radially arranged columnar epithelial cells (sugar)
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Zona reticularis
most of the adrenal cortex made of irregularly arranged cylindrical asses of epithelial cells(sex)
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Mineralcorticoids(aldosterone)
stimulates absorption of sodium by the kidneys and regulates water and salt balance
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Renin angiotensin aldosterone pathway
hormone system it regulates blood pressure and fluid balance
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Glucocorticoids (cortisol)
Effects of: increases breakdown of fats and proteins to generate blood glucose
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Gonadocorticoids(sex hormone)
may affect the onset of puberty pubic and auxiliary hair and sex drive
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epinephrine and nonepinephrine
adrenaline and noradrenaline
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the pancreas
secretes beta and alpha cells
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islet of Langerhans
secretes hormones of the pancreas
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alpha cells
secretes glucagon in response to lower level of glucose
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beta cells
produce insulin
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glucagon
increases blood sugar
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insulin
decreases blood sugar by making cell absorbs sugar otherwise It would stay in the bloodstream
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hypoglycemia
deficiency of glucose in the blood
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hyperglycemia
too much glucose in the blood
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ovary
female reproductive organ in which estrogen and progesterone are produced
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estrogen
development and maintenance of female characteristics
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progesterone
stimulate the uterus to repair for pregnancy
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testes
this is testosterone
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testosterone
stimulates the development of mail secondary sexual characteristics
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pineal gland
a pea-sized mass of tissue behind the third ventricle secreting melatonin
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melatonin
aids with sleep
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other hormone-producing structures
adipose cells pockets of cells in the walls of the small intestine stomach kidneys and heart
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