bio ppl

Griffith
- first to experiment with R and S cells
- killed S cells w/ heat and mixed with R cells = dead mouse
- transformation - concluded that something was transferring from S cells to R cells to make it kill the mouse
Avery
- after Griffith
- wanted to figure out which was the transforming agent - DNA, RNA, or protein
- 1. injected RNase into RNA - still transformed & killed
- 2. injected protease into Protein - still transformed & killed
- 3. injected DNase into DNA - DID NOT TRANSFORM & DID NOT KILL
Hershey-Chase
- After Avery
- add on to avery's experiment - find out if the heredity material the viruses transfer was protein or DNA
- injected radioactive isotopes into bacteriophages (sulfur to protein and phosphorus to DNA)
- lots of DNA in E. Coli and very little protein
- concluded that DNA is the hereditary molecule in viruses
Watson & Crick

figured out double helix & shape of DNA
Wilkins & Franklin

took x-ray diffraction photos of DNA to help watson & crick reveal shape of DNA

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Anonymous

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bio ppl

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bio

Updated

2014-02-20T03:30:01Z

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