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What is the generic name for Cymbalta?
Duloxetine
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What is the generic name for Savella?
Milnacipran
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What is the generic name for Effexor?
Venlafaxine
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What is the generic name for Pristiq?
Desvenlafaxine
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What I sthe generic name for Edronax?
Reboxetine
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What is the MOA of SNRIs?
Inhibit both SERT and NET
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Phenelzine brand name
Nardil
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Isocarboxazid brand name
Marplan
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Isocarboxazid (Marplan)
MAOI
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Tranylcypromine (Parnate)
MAOI
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Selegiline (Eldepryl)
MAOI
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What is the MOA of MAOIs?
Inhibit MAO in the cytoplasm and increase biogenic amine released
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Trazodone has what MAO?
Weak inhibitor of serotonin, partial agonist activity at post synaptic serotonin receptors
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What I is the MOA of Bupropion (Wellbutrin, Zyban)?
Inhibits DAT, some dopamine release enhancement
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What I is the MOA of Nefazodone?
5-HT2 blocker
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What I is the MOA of Mirtazapine?
Alpha 2 receptor and 5HT2/3 blocker, 5-HT and NE release enhancer
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SNRIs
Cymbalta (duloxetine), Savella (milnacipran), Effexor (venlafaxine), Pristiq (Desvenlafaxine)
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NaRIs
Edronax (Reboxetine)
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MAOIs
Phenelzine (Nardil), Isocarboxazid (Marplan), Tranylcypromine (Parnate) and Selefiline (Edepryl)
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With what drug class must patients be cautious about their diet and avoid food like Cheese, red wine and aged meats that contain tyramine?
MAOIs
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What drugs are contraindicated with MAOIs because they cause Biogenic amine release and may lead to increased biogenic amine neurotransmission?
SSRIs, TCAs, Dextromethorphran or Meperidine
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What is the MOA of ketamine?
N-methyl-D-Aspartate subtype Glutamine receptor antagonist, Changes the structures of glutamatergic synapses
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