pharm unit 3

  1. meds used for anxiety and insomia
    • Benzodiazepines
    • non-benzodiazepines sedatives
    • barbiturates
  2. Benzodiapepines
    • drugs of choice for anxiety and short term insomnia
    • can also treat seizures and ETOH withdrawl
    • Al have similar actions an adverse effects, but different onset and duration
    • Greater margin on safety than barbiturates
  3. Benzodiazepine ends with
  4. Mechanism of action Benzo
  5. benzo are given
  6. Adverse effects of benzo
    • Drowsiness
    • Dizziness
    • Lethargy
  7. Contrindications of Benzo
    • Pregnancy
    • COPD
    • hepatic and renal dysfunction
  8. lunesta has _____ than ambien
    half life

    • also rapid onset
    • causes dizziness, dry mouth
    • it is safe for long term use
  9. Buspar
    • takes several weeks to achieve max results
    • less likely to impair cognitive function
    • no dependence or withdrawl
    • few side effects
    • Mech of action Serotonin and Dopamine
  10. barbiturates
    • should be limited to 14 days when used as a sedative
    • overdose and withdrawal can be severe or fatal
    • rarely used for anxiety or insomnia because other drugs are safer
  11. Sonata
    shorter duration and faster acting tha ambien
  12. drugs used for seizure
    • barbiturates
    • benzodiazepine
    • Hydantoins
  13. Hyantoins
    • very irritating to veins
    • can only mix with NS
    • have to keep in range for best results
    • Contraindications: Gums grow, increases metabolism of steroids and warfarin and po contrceptives
  14. Cerebryx
    • only given IM, or IV
    • give to get pt stable than change to po med
  15. Drugs for depression
    • Tricyclic antidepressants
    • Selective Serotonin Reuptake inhibitors SSRI
    • Monoamine oxidase inhibitors MAOI
    • atypical antidepressants
  16. Anticholinergic
    slows everything down
  17. Tricyclic Antidepressants
    • used to be first line treatment
    • many adverse effects
    • 2-6 wks for full effect
    • anticholinergic effects
    • contrind: seizure, parkinsons, CV/Hepatic
    • interact: CNS depressants
  18. SSRI took place of ____
    TCAs because fewer side effects
  19. SSRI
    • given PO
    • longer half life
    • fewer adverse effects
    • may cause palpitations, sexual dys, wt gain, withdrawal is abruptly stopped
  20. do not give SSRI to pt with
    • bipolar disorder
    • seizures
  21. MAOI
    how does it work
    binds to MAO and prevents the destruction of epinephrine, NE, serotonin and dopamine
  22. MAOI given
  23. MAOI is
    not widely used because adverse effects

    contrind: schizophrenia, h/o CVA, HTN, renal and hepatic dys
  24. when taking MAOI you must avoid
    • certain foods
    • SSRI
    • TCAs
    • opiates
    • antidiabetic meds
  25. ADHD meds work by
    releasing NE and dopamine in the brian

    adverse effects: irritability, tachycardia, decreased app, decreased growth, elevated BP
  26. positive symptoms of schizophrenia
    • things that add to their normal function
    • hallucinations
    • delusions
    • paranoia
  27. negative symptoms of schizophrenia
    things that take away for normal functioning
Card Set
pharm unit 3
pharm test