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What do suppressor cells do?
Stop mutation
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What do malignant cells do
Mutate
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BMT regimen in preconditioning
5-10 days; needs to happen so they dont kill new cells (2 days are needed)
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Internal radiation
private room; limit time with visitors (30 min a day/6 feet away)
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Breast cancer prevention
self exam, mammogram, healthy diet, regular exercise
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Priority nursing dx for BM transplant
risk for infection, risk for bleeding
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Apoptosis
programmed cell death
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Excisional biopsy
removing entire lesion and removing adjacent normal tissue
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Incisional biopsy
on large tumors, wedge used to remove some tissue for analysis, problem increase risk of seeding and damage to healthy tissue
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Radiation therapy
go by none-no lotions, wash sites with water gently, do not remove marking, wear soft clothing, avoid head exposure
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Neupogen lab findings
Monitor WBC (help stimulate neutrophils)
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Chemo induced anemia
answer B
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Curative surgery
removes all cancer tissue
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Palliative surgery
focuses on improving the quality of life during the survival time not curing
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Reconstruction surgery
increases function, enhances appearance or both
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SVC syndrome
high dose of radiation to upper chest; metal stent in vena cava
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How do you know SVC treatment is working?
When symptoms are relieved, such as swelling and erythema in upper extremities
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How do you know when tumor lysis syndrome is working?
When labs, such as K return to normal
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How to transfer someone with metastis
consider pain, stabilize affected area
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Hypercalcemia tx
mithracycin, fluids and possibly dialysis
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Hypercalcemia
you know its working when pulse rate returns to normal but bounding
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Effect of radiation on cells
kills a few immediately but most within 24-48 hours
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Side effect of BM transplant
GFH disease
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Antineoplastic
chemo drug, patient is immunosuppressed
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DIC what decrease in labs
fibrinogen and platelets
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Thrombocytopenia
platelets are low causing abnormal bleeding
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Side effects of chemo
all counts decrease
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Tamoxifen
breast cancer hormonal drug; fights breast cancer, does not cure, blocks estrogen
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Hemophilia
clotting factors deficiency, bleeds into joints and muscle tissues heading to joint pain; heat makes inflammation worse-use ice
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Vaginal bleeding with uterine cancer
leg/flank pain-look for cancer
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Immune dysfunction
high pulse and orthostatic hypotension
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What are you looking for on a differential count?
Neutrophils, bands
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Hemolytic anemia
reticulated sites, increased RBC, platelets
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Lung cancer with metastisis
neuro changes
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Hodgkins lymphoma
most common assessment finding is a large but painless lymph node or nodes
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Brain tumor
change in LOC, dizziness, visual changes, headaches
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Acute lymphatic leukemia
Bone marrow shows abnormal chromosomes
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Polycythemia vera labs
increased K
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Polycythemia vera risk for
increased BP, headaches, chest pain, angina, SOB, thrombophlebitis, itchy skin
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Leukemia nutrition
small frequent meals high in protein and carbs; liwuid or semisolid
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B12 deficiency anemia
nervous system affected (leading to falls)
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Folate deficient anemia
green leafy veg, no effect on nervous system
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Hodgkins lymphoma and radiation
permanent sterility in male
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Sickle cell anemia and RBC difference
clotting and structure
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Multple myeloma labs
M Protein, serum monoclonal protein
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Leukemia
too many RBC, other cts are low
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Hemophilia
dont take aspirin
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Hodgkins disease education
teens-young adults, adults 50-60
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Multiple myeloma
malignant cells in para protein in blood or urine
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Neutropenic precautions
no raw food
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Vitals in all types of anemia
fatigue
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Chronic anemia
alcohol addiction
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B-12 diet deficienct
macrocytic, dairy and animal proteins
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Acute leukemia history assessment
age, occupation, previous illness, exposure to radiation
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S/S of B12 deficiency
tired, light headedness, weakness, rapid heartbeat, pale, easy bleeding or bruising, stomach upset, diarrhea or constipation
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Path mechanism in aplastic anemia
deficiency of circulating RBC because of failure of the bone marrow to produce these cells; usually occurs with leukopenia and thrombocytopenia
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VonWillibrand
normal platelet count
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Hemophilia in child lab value
PTT
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Sickle cell crisis
hydration, pain, infection
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Hydroxyurea
reduces the number of sickling and pain episodes
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Labs for polycythemia vera
increase in H&H and platelets and RBC
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Multiple myeloma standard treatment
chemo, noncurable, can go dormant
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Worst skin cancer
squamous
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Benz jones/Mprotein in multiple myeloma
benz jones
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Folate needed for
RBC production
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