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Buerger's Disease
- Also called thromboangitis obliterans
- This condition causes inflammation and clots in the blood vessels in your arms and legs
- Signs and symptoms can include pain in hands, arms, feet and legs, and ulcers on fingers and toes
- This disorder is strongly associated with cigarette smoking
- Jewish males 20 to 40 years old
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Takayasu's Arteritis
- This form of vasculitis includes the largest arteries in the body, including the aorta
- Typically occurs in young women (Asian females)
- Signs and symptoms include back pain, arm weakness or pain with use (claudication), decreased or absent pulses, lightheadedness, headaches, and visual disturbances
- Usually require pre-op corticosteroids
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Kawasaki Disease
- Also known as mucocutaneous lymph node syndrome
- This condition most often affects children younger than 5 years of age
- Signs and symptoms include fever, skin rash and eye inflammation
- Intraop complications: MI, Cerebral hemorrhage
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Giant Cell Arteritis (GCA): Temporal Arteritis
- This condition, which usually occurs in people older than 50, is an inflammation of the arteries in your neck, upper body, arms, and — most often — head, especially the temples
- Most common type of vasculitis in the United States
- Can cause headaches, scalp tenderness, jaw pain, blurred or double vision, and even blindness
- Often associated with polymyalgia rheumatica and stiffness and aching in the neck, shoulder and hip girdle regionsTreatment is corticosteroids
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Raynaud’s Phenomenon
- Cold induced arterial spasm of extremities
- Often found in adult females: associated with scleroderma, SLE
- Necessary to maintain intraoperative body temperature and avoid vasoconstrictors with regional anesthesia
- Treatment is reserpine, guanethidine and stellate ganglion block
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Wegener's Granulomatosis
- This condition causes inflammation of the blood vessels in your nose, sinuses and throat, lungs, and kidneys.
- Signs and symptoms can include shortness of breath, nasal pain and stuffiness, nosebleeds, and ulcers in your nose
- Also involves multiple organ systems with necrotizing granulomas in inflamed vessels
- Patients may be immuno-suppressed due to treatment with cyclophosphomide
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Polyarteritis Nodosa
- This form of vasculitis affects small to medium sized blood vessels in many different parts of the body, including your skin, heart, kidneys, peripheral nerves, muscles and intestines
- Signs and symptoms include purpura, skin ulcers, muscle and joint pain, abdominal pain, and high blood pressure (hypertension)
- Patients may also exhibit myocardial ischemia, peripheral neuropathies, glomerulitis, seizures
- Found in females 20 to 60 years of age
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Moyamoya Disease
- Presents as a narrowing or occlusion of both internal carotid arteries
- May cause TIAs in children and intracerebral hemorrhage and intracranial aneurysms in adults
- May pose a challenge intraoperatively between balancing cerebral blood flow and cerebral O2 requirements
- Postop complications may include hypo and hyper capnia, hypotension and hypovolemia
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