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monosaccharide:
5C - ribose/deoxyribose
6C - glucose/ fructose/ galactose
(aldehyde) (ketone)
disaccharide:
sucrose = glucose + fructose
lactose = galactose + glucose
polysaccharides:
glycogen (store energy in liver) = animal starch stored in liver
α linkage
cellulose = structural (tree bark) fibrous sugar
β linkage
Cholesterol:
rigid ring struct
1. signaling molecules --> STEROIDS (testosterone)
2. structural --> broaden range of temp that memb can maintain fluidity
GIBBS FREE ENERGY EQ
ΔG = ΔH - TΔS
ΔG - total NRG
ΔH - potential NRG (bond NRG)
enthalpy NRG in bonds
TΔS - kinetic
(-) heat rel
(+) heat taken in
T = kelvin
ΔS = entropy disorder
ΔG = dictate, favorability of rxn
(-) favorable (NRG being rel)
(+) unfavorable
ΔG = 0
Can affect ΔG?
EQUILIBRIUM = dynamic (stuff moving back & forth)
1. intrinsic prop of prod & reactants
2. relative [prod][react]
Kinetics ≠ Thermo
enzymes?
(speed does not relate to favorability of rxn)
kinetics → speed = v
Ea = energy of activation; "speed bump" need to go so fast to get over
catalyst = ↓Ea
K
m
=
[S] @ which V=1/2 Vmax
- strength of affinity b/w enzy & subst (E/S)
↑Km = ↓affinity
↓Km = ↑affinity
INHIBITORS:
competitive = bind to active site
↑km
overcome by ↑[S]
noncompetitive = binds
allosterically
↓Vmax
NOT
overcome by ↑[S]
Cellular Respiration:
oxidizing = glucose (can do others to)
e- carriers =
NAD+/NADH
FAD/FADH
2
CELLULAR RESPIRATION CHART
GLYCOLYSIS:
hexo
kinase
= locks gluco into cell
phospho
fructose kinase:
COMMITTED STEP
allosterically
↑
AMP
/
ATP =
↑PFK
↓
AMP
/
ATP
= ↓PFK
Fermentation:
anaerobic regeneration
NAD+
animals yeast
↓ ↓
lactic acid EtOH
Pyruvate Dehydrogenase Complex:
1st decarboxylation
same regulations
PFK
AMP
/
ATP
2 NADH
Citric Acid Cycle:
2C 4C 6C
Acetyl-CoA + OAA -----> Citric Acid
citric synthase
oxaloacetic acid
x4 oxidative decarboxylations
6 NADH
2 FADH
2
2 GTP
ETC
Glycolysis # of NADH/ATP
2 NADH --------> 3 ATP
1.5
-2 ATP
5 ATP
+4 ATP
PDC # of NADH/ATP
2 NADH ------> 5 ATP
TCA
6 NADH ---2.5---> 15 ATP
2 FADH ---1.5---> 3 ATP
2 GTP -------------> 2 ATP
Total ATP
[glycolysis, PDC, TCA]
30 ATP (euk)
32 ATP (prok)
PHOTOSYNTHESIS
Photoautotrophs -
plastids:
thylakoid memb = coin
grana = stack of coins
stroma = area outside grana
take NRG sun --> harness to
make
a more reduced/complex molecule
3 CO2 →
3C
(sugar)
Photosynthesis 2 parts:
1. Light dependent rxn making
NADPH/ATP = power light independent
↓
anabolism
2. Light independent = dark cycle
NADPH + ATP + CO2 → G-3P + ADP + NADPH + H2O
G-3P: glyceraldehyde-3-P
RuBisCO
Photosynthesis glucose
6 CO2
18 ATP
12 NADPH
CENTRAL DOGMA
Mutation:
Replication:
DNA pol (prok)
III
II
I
III = 5' → 3' polymerase
3' → 5' exonuclease
II = unknown
I = 5' → 3' poly
5' → 3' exonuclease
TRANSCRIPTION
DNA → RNA
-----------------------> RNA (+)
<----------------------- (-) antisense
DNA
-----------------------> (+) sense
transcription
START
codon
AUG =
MET
STOP codon
UAA
AGA
UAG
ribosomes
#
3 sites
prok 70s = 50s + 30s
euk 80s = 60s + 40s
A = aminoacyl (arrival)
P = peptidyl site
E = exit
RNA pol (euk)
I
II
III
I = rRNA
II = mRNA*
III = tRNA
Virus -->
Lytic
(4)
(1) get into (invade) cell
(2) get genome free
(3) replication
(4) rupture & escape
humans =
excreted
Virus -->
Lysogeny
(5)
(1) Get into cell
(2) Get genome free
(3)*Inserts genome into host genome
(4) Cell replicates/ divides
- free copies
- protects from immune attracts
(5)
Activated → replicating
↓
enter lytic phase
autotroph =
fixes CO2
phototroph =
uses light to do something
chemotrophs =
use nonorganic as
e-
source
heterotrophs =
use organic as
carbon
source
obligate anaerobe =
use only O2
facultative anaerobe =
use O2 but don't need to
tolerate anaerobe =
don't use O2 but tolerate
obligate anaerobe =
O = KILLS
Author
napoleon
ID
25813
Card Set
Biol 1
Description
Biol Class 1
Updated
2010-07-13T01:24:13Z
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