anti inflammatories.txt

this subtance is the mediator of the inflammatory process

this enzyme aids in prostaglandin synthesis

Anti-inflammatory meds include:

what can be done to avoid drug interactions/ adverse effects?

COX enzyme --> prostaglandin synthesis --> mediation of inflammatory process

How does aspring work in this process?

: pyretic

Indications for asprin:

NSAIDS is a non-selective COX inhibitor therefore inhibits both COX-1 (good) and COX-2 (bad) enzymes.

what is the differnce between asprin and NSAIDS?

this anti-inflammatory drug may cause edema especially in patients with renal dysfunction and heart disease.

COX-1 inhibition --> decreased urine output --> fluid retention and edema

COX-2 inhibitors were discontinued due to fatal cardiac effects. these included:

these drugs are potent anti-inflammatories:

these are naturally occurring anti-inflammatories from the adrenal cortex

Indications for glucocorticosteriods:

these drugs inhibit parts of the inflam process including:

capillary dialation

edema formation

leukocyte and macrophage migration to area