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DMARD's: Disease modifying anti-rheumatic drugs are used with active, continuing inflammatory disease.
Methotrexate
Anti-cytokines
an enzyme inhibiting drug. used as an anti-cancer agent as well as DMARD
Methotrexate
This DMARD
binds
with TNF (anti-human tumor necrosis factor-alpha) and
inactivates
it.
Anti-cytokines
This DMARD inhibits T & B cell activity involved in the autoimmune process:
Leflunomide (Arava)
This DMARD is used in
combo
with methotrexate:
infliximab
This DMARD
blocks
interleukin receptors which
diminshes
bone erosion and cartilage destruction:
Anakinra (Kineret)
these are side affects of what DMARD's:
mental status changes
retinopathy
muscle weakness with decreased DTR's
Anti-malarials
these are side affects of what DMARD's:
GI problems
skin problems
blood disorders
bone marrow depression
sulfa drugs, penicillamine, and imuran (immunosuppressant)
a potent immunosuppressant that reduces T & B cell activation:
cyclosporine (Neoral)
***Look for any change in RA or general health status due to many possible drug interactions***
Author
BELISA78
ID
25799
Card Set
DMARDs.txt
Description
review of disease modifying anti-rheumatic drugs
Updated
2010-07-06T05:05:43Z
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