antibiotics

pfizerpen, bicillin LA, veetids

• gram (+): strep
• mouth anaerobes

penicillinase resistant penicillins

gram (+): MSSA, strep

aminopenicillins

• gram (+): strep
• gram (-): h. influenza, e.coli, proteus, salmonella, shigella

augmentin & unasyn

• gram (+): beta lactamase producing MSSA
• gram (-): h. influenza, m. catarrhalis, e. coli, k. pneumoniae
• anaerobes

zosyn & timentin

antipseudomonal penicillins

same as augmentin plus pseudomonos

• NVD
• hypersensitivity
• interstitial nephritis
• hemolytic anemia

• cefadroxil
• cefazolin
• cephalexin

• gram (+): staph, strep
• gram (-): e. coli, p. mirabilis, k. pneumoniae

cefaclor, cefotetan, cefoxitin, cefprozil, cefuroxime

• gram (+): staph, strep
• gram (-): e. coli, p. mirabilis, k. pneumoniae, acinetobacter, enterobacter, neisseria, serratia, h. influenza

cefdinir, cefixime, cefoperazone, cefpodoxime, ceftazidime, ceftibuten, ceftizoxime, ceftriaxone

• limited gram (+)
• gram (-): e. coli, p. mirabilis, k. pneumoniae, acinetobacter,
• enterobacter, neisseria, serratia, h. influenza plus more
• -ceftazidime: pseudomonas

cefepime

• gram (+) and (-)
• pseudomonas

duricef

1st gen

ancef

1st gen

keflex

1st gen

raniclor

2nd gen

2nd gen

mefoxin

2nd gen

cefzil

2nd gen

• ceftin
• zinacef

2nd gen

omnicef

3rd gen

suprax

3rd gen

cefobid

3rd gen

vantin

3rd gen

claforan

3rd gen

• fortaz
• tazicef

3rd gen

cedax

3rd gen

cefizox

3rd gen

rocephen

3rd gen

maxipime

4th gen

carbapenems

• broad spectrum (+) and (-)
• all work against pseudomonas except ertapenem

may cause seizures

doribax

invanz

primaxin

merrem

azactam. monobactam

only effective against gram (-) & pseudomonas

• amikacin, gentamicin, kanamycin, neomycin, streptomycin, tobramycin
• amikin, garamycin/gentak, kantrex, neo-fradin, generics, tobi/tobrex

bacteriocidal concentration dependent killing

• *gram (-): kleb, p. mirabilis, acinetobacter, serratia, pseudomonas
• *synergistic with pcn or vanc against gram (+): staph, strep, enterococcus
• *streptomycin & amikacin: mycobacteria

nephrotox, ototox

• azithromycin, clarithromycin, erythromycin, telithromycin
• zithromax/zmax, biaxin, EES/eryped/erytab/pce/erythrocin

• gram (+): strep (azith and clarith are better)
• gram (-)
• atypicals: chlamydia, legionella, mycoplasma
• azith & clarith: mycobacteria

• NVD
• QT prolongation
• phlebitis (erythro IV)

• demeclocycline, doxycycline, minocycline, tetracycline
• declomycin, doryx/vibramycin, dynacin/minocin, sumycin

gram (+), (-), and atypicals

• NVD
• photosensitivity
• phlebitis
• vertigo (mino)

discolors teeth of children

tygacil. its a glycycline.

gram (+): MSSA, MRSA, VRE

adrs: NVD, photosensitivity

zyvox. its an oxazolidinone. weak MAOI

gram (+): VRE, MRSA, resistant strep

adrs: NVD, HA, myelosuppression, peripheral/optic neuropathy, seizures

synercid. its a streptogramin

VRE, MRSA, MSSA

adrs: NVD, muscle/joint pain, increases bilirubin

• ciprofloxacin, gemifloxacin, levofloxacin, lomefloxacin, moxifloxacin, ofloxacin
• cipro/proquin, factive, levaquin, maxaquin, avelox, floxin

• gram (+), (-), atypicals
• cipro: pseudomonas

not for people <18 YO

ND, photosensitivity, tendon rupture, BG changes, peripheral neuropathy, seizures, QT prolongation

• sulfadiazine, sulfamethoxazole/trimethoprim, sulfisoxazole
• generics, bactrim/septra, gantrinsin

• gram (+) including MSSA/MRSA
• gram (-)
• sulfadiazine: toxoplasmosis

NVD, rash (SJS), photosensitivity, folate deficiency, hypoglycemia

not in G6PD deficiency

cubicin

gram (+): MSSA, MRSA, VRE

adrs: ND, muscle pain/weakness

generics

• gram (+): VRE
• gram (-)

adrs: NVD, myelosuppression, gray baby syndrome, optic neuritis

cleocin, clindesse, evoclin

gram (+) anaerobes

adrs: NVD, pseudomebranous colitis

flagyl, metrogel, noritate, vandazole

anaerobes

adrs: ND, confusion, dizziness, peripheral neuropathy, metallic taste, DSR

vancocin

• gram (+): MSSA, MRSA
• c. diff

adrs: red man syndrome, nephrotox, ototox (?)