Perioperative Anesthesia Overview

  1. Some Components of “Balanced General Anesthesia”
    • 1. Unconsciousness (General anesthesia is a reversible drug-induced coma.)
    • 2. Analgesia (pain relief)
    • 3. Immobility (muscle relaxation)
    • 4. Hemodynamic stability (Many general anesthetics, spinal anesthesia, and epidural anesthesia all tend to drop the BP.)
  2. Bad side effects of GA
    • Resp. Depression
    • Nausea and Vomitting
    • Seizure
    • Cardiovascular Instability
  3. Resp depression is common with...
    • Propofol
    • Inhaled anesthetics
    • Fentanyl
  4. Nausea and vomitting common with...
    • Fentanyl 
    • Nitrous oxide 
    • Volatile inhaled anesthetics (isoflurane, desflurane, sevoflurane)
  5. What can be given as anti-emetic
    Ondansetron (ZofranR), a 5HT3-receptor antagonist, is often given IV to prevent or to treat nausea and vomiting.
  6. What 2 drugs are discouraged with use in those with seizure disorders?
    etomidate and sevoflurane
  7. iEphedrine
    • 1. Classification: Sympathomimetic amine
    • Think of it as a “weak epinephrine”
    • Indirect norepinephrine release
    • Some direct action
    • 2. Clinical Use: Increase BP and HR
    • Rx. of hypotension
    • 3. Clearance: Mostly renal
    • 4. Correcting for SE: Titrate carefully ! Increases BP, HR, arrhythmias
Card Set
Perioperative Anesthesia Overview
Final TUSPM Introtosurg