TB

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when do primary and secondary TB occur
- primary- children and first time
- secondary- adults and reinfection and reactivation
what is potts diseases

midthoracic infection with anterior erosion of vertical bodies
what are the two test used for detection of TB
- TST-PPD
- IGRAs (gold, gold in tube, T.spot)
when are IGRAs testing preferred
- pts who have a poor return rate
- pts who recieved BCG vaccince
when is TST the preferred method for testing

children under the age of 5
what is another name for the fluorochrome stain

Auramine Rhodamine Stain
which stain is used to comfirm cultures

acid fast stain
recommendation for INH in pregnant women
- increase risk for hepatitis
- do not give until 6 months post partum
how long should pts with fibrotic nodular lesions or evidence of silicosis, without evidence of active TB, recieve prophylactic tx

12 mths with INH or 4 mths with rifampin + INH
how long should HIV infected individuals with positive PPDs be treated

min 6 months
adverse rx to INH
- hepatotox
- peripheral neuropathy
MOA of INH

inhibits cell wall synthesis
how does antacid affect the absorption of INH

decreases absorption
MOA of rifampin

inhibits RNA polymerase
which TB drug causes fluid discoloration

rifampin
AE of rifampin
- hepatitis
- thrombocytopenia
- flu like sx
MOA of EMB

inhibit mycolic incorporation into mycobacterium cell walls
ethambutol is CI in which group

children
MOA of streptomycin

binds 30s ribosomal subunit inhibiting bacterial protein synthesis
a positive skin test can be seen in which type of leprosy

tuberculoid leprosy
types of diagnosis of leprosy
- lepromin skin test
- skin lesion biopsy
- skin scraping exam
tx for leprosy
- rifampicin
- dapsone
- clofazimine
duration of tx for leprosy

over 12 months
tx for MAC
- prolonged tx with biaxin or zithromax
- plus EMB and rifabutin

Author

alvo2234

251182

Card Set

Description

final

Updated

2013-12-06T04:20:00Z

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