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All DNA Viruses discussed in this lecture are all dsDNA except which ONE?
Parovirus
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Adenovirus
Shape
Diseases caused:
Respiratory disease, eye inf., GI disease
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Hepadnavirus
Shape
Disease Caused
dsDNA has short ss region
- Icosahedral core
- enveloped
Hep B (surface & core Ag) (vaccine engineered)
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Herpesviruses
Shape
Diseases
- Icosahedral nucleocapsid
- enveloped
HSV 1&2, VARICELLA, CMV,HHV 6-8,EBV,
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Varicella
Disease
Stain/Identification
Chicken pox & Shingles
Tzanck stain of lesion - Giant Cells
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EBV
Disease commonly associated with EBV
Lab test
Burkitts Lymphoma
Serology: early Ag, Viral capsid Ag, Nuclear Ag
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HHV - 6,7, & 8
Diseases found with each
- 6:
- ~Exanthema / Roseaola
- **6th disease
- Molecular test
- 7:
- Small percentage of reseaola
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Papillomavirus
Diseases:
- Warts
- Cervical cancer
- Laryngeal carcinoma
Molecular assays
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Paroviruses
Shape
Diseases
Test
Small non enveloped
- *B19
- 5ths disease
- Aplastic crisis
Molecular assay
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Poxviruses
Size
Shpae
- replicated in cytoplasm
- LARGEST virus
- Complex:
- Brick shape & Lipid envelope
Resistant to many environmental factors
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Disease associated with poxviruses
Small pox - Variola
Vaccinia: vaccine
Moneypox: rare zoonitic Africa
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