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adaptive immunity
Ability to recognize and remember specific antigens and mount an attack on them
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adenoids
Mass of lymphatic tissue in the nasopharynx
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antibody
Protein produced by B cells to destroy antigens
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antigen
Substance that the body recognizes as foreign; evokes an immune response
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axillary nodes
Lymph nodes in the armpit
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B cell (B lymphocyte)
Lymphocyte that matures into a plasma cell to secrete antibodies
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cell-mediated immunity
T cells that respond to antigens and destroy them
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cervical nodes
Lymph nodes in the neck region
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complement system
Proteins in the blood that help antibodies and kill their target
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cytokines
Proteins secreted by cytotoxic T cells to aid in antigen destruction
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cytotoxic T cell (CD8 +T cell)
Lymphocyte that directly kills antigens
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dendritic cell
Antigen-presenting cell; shows T and B cells what to attack
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helper T cell (CD4+ T cell)
Lymphocyte that aids B cells and stimulates T cells
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humoral immunity
- B cells produce antibodies after exposure to specific antigens; type of adaptive
- immunity
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immunity
Body’s ability to resist foreign organisms and toxins that damage tissues and organs
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immunoglobulins
Antibodies secreted by plasma cells in response to the presence of an antigen
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immunotherapy
Use of immune cells, antibodies, or vaccines to treat or prevent disease
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inguinal nodes
Lymph nodes in the groin region
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interferons
Proteins secreted by T cells and other cells to aid and regulate the immune response
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interleukins
Proteins that stimulate the growth of B and T lymphocytes
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interstitial fluid
Fluid in the spaces between cells; becomes lymph in lymph capillaries
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lymph
- Thin, watery fluid within lymphatic vessels and collected from tissues throughout the
- body
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lymph capillaries
Tiniest lymphatic vessels
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lymphoid organs
Lymph nodes, spleen, and thymus gland
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lymph node
Collection of stationary solid lymphatic tissue along lymph vessels
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lymph vessel
Carrier of lymph throughout the body
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macrophage
Large phagocyte found in lymph nodes and other tissues of the body
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mediastinal nodes
Lymph nodes in the area between the lungs in the thoracic cavity
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mesenteric nodes
Lymph nodes in the mesentery
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monoclonal antibody
An antibody produced in a laboratory to attack antigens and to destroy cells
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natural immunity
Protection that an individual is born with to fight infection
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paraaortic nodes
Lymph nodes near the aorta in the lumbar area of the body
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plasma cell
Lymphocyte that secretes antibodies; matures from B lymphocytes
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Right lymphatic duct
Vessel in the chest that drains lymph from the upper right part of body; empties into large neck vein
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Spleen
Organ in the left upper quadrant of the abdomen that destroys worn-out RBCs, activates lymphocytes, and stores blood
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suppressor T cell (Treg)
Lymphocyte that inhibits the activity of B and T cells
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T cell (T lymphocyte)
- Lymphocyte that acts directly on antigens to destroy them or produces chemicals toxic to
- antigens
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tolerance
- Ability of T lymphocytes to recognize and accept the body’s own antigens as “self” or
- friendly
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thoracic duct
Drains lymph from the lower and left side of body; empties into large veins in neck
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thymus gland
Lymphoid organ in the mediastinum that conditions T cells to react to foreign cells
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tonsils
Masses of lymphatic tissue in back of the oropharynx
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toxin
Poison; a protein produced by certain bacteria, animals, or plants
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vaccination
- Exposure of an individual to an antigen that provokes an immune response that will
- destroy any cell with the antigen and will protect against infection
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vaccine
- Weakened or killed microorganisms, toxins, or other proteins given to induce immunity to
- infection or disease
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AIDS
Acquired ImmunoDeficiency Syndrome
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ELISA
test to detect anti-HIV antibodies
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HIV
Human ImmunoDeficiency Virus
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Immunodeficiency
Acquired immunodeficiency syndrome (AIDS)
- - Destroys T helper cells (CD4+
- cells)
- Opportunistic infections
- Malignancies
(Kaposi sarcoma, wasting syndrome)
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Reverse transcriptase inhibitors
(RTI)
inhibit viral enzyme called reverse transcriptase.
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Protease inhibitors
inhibit viral proteolytic enzyme
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Lymphoma
malignant tumor of lymph nodes and lymph tissue
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Multiple Myeloma
malignant tumor of bone marrow cells
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Thymoma
malignant tumor of the thymus
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