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antibiotic
chemical produced by one microbe that can harm another microbe
antimicrobial
any agent that can harm microbes
bacteriocidal drug
drugs that kill microbes
bacteriostatic drug
drugs that slow microbe production
chemotherapy
using chemical against invading organisms
selective toxicity
no injury to cell host only target organism
narrow spectrum antibiotics
work only on a few microbes
broad specturm antibiotics
active against a wide variety of microbes
nosocomial infection
infection acquired at hospital
2 ways resistance acquired
spontaneous mutation
conjugation
suprainfection
new infection appears during course of treatment for a primary infection
minimum inhibitory concentration
lowest concentration of antibiotic that produces complete inhibition of bacterial growth
minimum bacteriocidal concentration
lowest concentration of drug that kills 99.9% bacterial colonies
kerniterus
sever neurologic disorder caused by displaced billirubin from protein plasma
level of antibiotic at site of infection
4-8 times the MIC
beta lactam
antibiotic that destroy beta lactam ring or wall of bacteria
penicillin G
bet-lactem
ADR
allergies
cephalexin (keflex)
beta-lactam
ADR
bleeding
allergies
INTER
disulfiram
probenecid
Imipenem (primaxin)
beta-lactam
ADR
allergies
gastroinstestinal
suprainfection
vancomycin (vancocin)
red man syndrome
ototoxicity
infusion reaction
tetracycline hydrochloride (sumycin)
Gastrointestinal
tooth discoloration
suprainfection
INTER
oral contriceptives
Milk calcium iron magnesium supplements
Erythromycin (E-mycin)
bacteriostatic
ADR
gastrointestinal
thrombophlebitis
INTER
antihystamines
theophyline
warfarin
carbamazepine
Gentamycin (garamycin)
ototoxicity
nephrotoxicity
neuromuscular blockage
trimethoprim-sulfamethoxazole (TMP-SMZ)
bactrim
folic acid
stevens-johnson
blood dyscrasias
crystalluria
kernicterus
nitrofurantoin (macrodantin)
bacteriostatic low dose
bacteriocidal high dose
ADR
GI
blood dyscrasias
isoniazid (INH)
antituberculosis drug
neuropathy
hepatotoxicity
INTER
phenytoin
alcohol
dapsone (leprosy)
anti-hansens disease
folic acid
ADR
hepatotoxicity
GI
INTER
warfarin
oral contraceptive
NNRTI for HIV
acyclovir (zovirax)
prevents DNA reproduction
ADR
phlebitis
nephrotoxicity
INTER
granulocytopenia
thrombocytopenia
reproductive toxocity
ciprofloxacin (cipro)
stop dna replication
ADR
GI
achillies tendon rupture
suprainfection
INTER
warfarin
theophyline
milk iron mg dairy
metronidazole (flagyl)
bacteriocidal anaerobic
ADR
metallic taste
dark urine
cns symptoms
INTER
alochol
disulfiram
warfarin
amphoterin B deoxycholate
(fungizone)
antifungal
ADR
infusion reaction
nephrotoxicity
hypokalemia
bone marrow suppresion
ketoconazole (nizarol)
hepatotoxicity
ADR
gynecomastia
irregular menstral flow
INTER
flucytosine
aminoglycosides
B cells
produce antibodies
Immunosuppressants
reduce production of B cells and
cytotoxic T cells CD8
immunostimulant
boost the immune system
assist body to kill cancer cells
macrophages and dendritic cells
phagocytosis
cytolytic T lymphocytes
(CD8)
destroy target cells directly and killing microbe
Helper T cells (CD4)
activate B cells
delayed hypersensitivity reaction (DTH)
Natural Immunity
innate-native immunity
present at birth
specific acquired immunity
a persons body produce antibodies to protect itself
active acquired immunity
having the infoection
admin of vaccine or toxoid
passive acquired immunity
admin of preformed antibodies
immunoglobulins
acquired immunity (2)
active by vaccinations
passive by immunoglobulins
alt name for antibodies
immunoglobulins
gamma globulins
5 classes of antibodies
IgA
IgD
IgE
IgG
IgM
antigen
molecules that trigger specific immune response and become targets if those responses
toxoid vacccine
DTaP vaccine
live vaccines
MMR
Varicella
Influenza
Rotavirus
guillain- barre syndrome
autoimmune disorder of peripheral nervous system
caused by flu vaccine
MMR
local reaction
ADR
allergy to eggs gelatin neomycin
Dtap
encephalopathy 7 days after
seizure
reyes syndrome
aspirin to kids
tetanus booster
every 10 years
Interferon alfa (interleukin-2)
stop cancer cells
ADR
alopecia
bone marrow suppresion
cardiotoxicity
neurotoxicity
hypotension
INTER
cyclosporine
hepatotoxic
nephrotoxicity
grapefruit juice
prednisone
glucocorticoids
ADR
bone loss
adrenal impariment
fluid retention
INTER
diuretic
NSAIDs
azathioprine
cytotoxic drug
bone marrow depression
allopurinol
antihistamine
1st generation
dephenhydramine (benadryl)
dimenhydrinate (dramimine)
antihistamine
2nd generation
loratadine (claritin)
fexofenadine (allegra)
cetirizine (zyrtec)
chemotherapy agents
anticancer agents to kill cancer cells
antitumor antibiotics
doxorubicin (adrimycin)
breast cancer antibiotic
antiestrogen (tamoxifen)
prostate cancer antibiotic
leuprolide (lupron)
chemotherapy side effects
alopecia
bone marrow suppression
GI discomfort give antiemetic
extravasation of vesicants
antihistamine
(h1 antagonist)
neuroleptic malignant syndrome
fever
muscular rigidity
autonomic dysfunction
altered mental status
steven-johnson syndrome
epidermis detaches from dermis
Author
blkbunny20
ID
24570
Card Set
dmrn108
Description
antimicrobial immune system
Updated
2010-06-27T19:06:24Z
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