dmrn108

chemical produced by one microbe that can harm another microbe

any agent that can harm microbes

drugs that kill microbes

drugs that slow microbe production

using chemical against invading organisms

no injury to cell host only target organism

work only on a few microbes

active against a wide variety of microbes

infection acquired at hospital

• spontaneous mutation
• conjugation

new infection appears during course of treatment for a primary infection

lowest concentration of antibiotic that produces complete inhibition of bacterial growth

lowest concentration of drug that kills 99.9% bacterial colonies

sever neurologic disorder caused by displaced billirubin from protein plasma

4-8 times the MIC

antibiotic that destroy beta lactam ring or wall of bacteria

• bet-lactem
• ADR
• allergies

• beta-lactam
• ADR
• bleeding
• allergies
• INTER
• disulfiram
• probenecid

• beta-lactam
• ADR
• allergies
• gastroinstestinal
• suprainfection

• red man syndrome
• ototoxicity
• infusion reaction

• Gastrointestinal
• tooth discoloration
• suprainfection
• INTER
• oral contriceptives
• Milk calcium iron magnesium supplements

• bacteriostatic
• ADR
• gastrointestinal
• thrombophlebitis
• INTER
• antihystamines
• theophyline
• warfarin
• carbamazepine

• ototoxicity
• nephrotoxicity
• neuromuscular blockage

• folic acid
• stevens-johnson
• blood dyscrasias
• crystalluria
• kernicterus

• bacteriostatic low dose
• bacteriocidal high dose
• ADR
• GI
• blood dyscrasias

• antituberculosis drug
• neuropathy
• hepatotoxicity
• INTER
• phenytoin
• alcohol

• folic acid
• ADR
• hepatotoxicity
• GI
• INTER
• warfarin
• oral contraceptive
• NNRTI for HIV

• prevents DNA reproduction
• ADR
• phlebitis
• nephrotoxicity
• INTER
• granulocytopenia
• thrombocytopenia
• reproductive toxocity

• stop dna replication
• ADR
• GI
• achillies tendon rupture
• suprainfection
• INTER
• warfarin
• theophyline
• milk iron mg dairy

• bacteriocidal anaerobic
• ADR
• metallic taste
• dark urine
• cns symptoms
• INTER
• alochol
• disulfiram
• warfarin

• antifungal
• ADR
• infusion reaction
• nephrotoxicity
• hypokalemia
• bone marrow suppresion

• hepatotoxicity
• ADR
• gynecomastia
• irregular menstral flow
• INTER
• flucytosine
• aminoglycosides

produce antibodies

• reduce production of B cells and
• cytotoxic T cells CD8

• boost the immune system
• assist body to kill cancer cells

phagocytosis

destroy target cells directly and killing microbe

• activate B cells
• delayed hypersensitivity reaction (DTH)

present at birth

a persons body produce antibodies to protect itself

• having the infoection
• admin of vaccine or toxoid

• admin of preformed antibodies
• immunoglobulins

• active by vaccinations
• passive by immunoglobulins

• immunoglobulins
• gamma globulins

• IgA
• IgD
• IgE
• IgG
• IgM

molecules that trigger specific immune response and become targets if those responses

DTaP vaccine

• MMR
• Varicella
• Influenza
• Rotavirus

• autoimmune disorder of peripheral nervous system
• caused by flu vaccine

• local reaction
• ADR
• allergy to eggs gelatin neomycin

• encephalopathy 7 days after
• seizure

aspirin to kids

every 10 years

• stop cancer cells
• ADR
• alopecia
• bone marrow suppresion
• cardiotoxicity
• neurotoxicity
• hypotension
• INTER

• hepatotoxic
• nephrotoxicity
• grapefruit juice

• glucocorticoids
• ADR
• bone loss
• adrenal impariment
• fluid retention
• INTER
• diuretic
• NSAIDs

• cytotoxic drug
• bone marrow depression
• allopurinol

• dephenhydramine (benadryl)
• dimenhydrinate (dramimine)

• loratadine (claritin)
• fexofenadine (allegra)
• cetirizine (zyrtec)

anticancer agents to kill cancer cells

doxorubicin (adrimycin)

antiestrogen (tamoxifen)

leuprolide (lupron)

• alopecia
• bone marrow suppression
• GI discomfort give antiemetic
• extravasation of vesicants

• fever
• muscular rigidity
• autonomic dysfunction
• altered mental status

epidermis detaches from dermis