Lymphatic System (notes)

• 1. Organs
• 2. Ducts
• 3. Nodes

• 1. collect and return interstitial fluid to blood to maintain fluid balance
• 2. defend body by maturing lymphocytes
• 3. absorb lipids form the intestine and transport them to the blood

fluid and protein that has been squeezed out the blood

lymph Capillaries-->lymph Vessels-->lymph Trunks--> lymphatic Ducts

• Primary Lymphatic Organs & Tissues (sites where stem cells divide and become immunocompetent):
• 1. Red Bone Marrow
• 2. Thymus
• Secondary Lymphatic Organs & Tissues (where most immune responses occur):
• 1. Lymph Nodes
• 2. Spleen
• 3. Lymphatic Nodules

• encapsulated oval structures, usually in group
• filters to remove damaged cells and microorganisms
• are the sire of proliferation of Bcells and Tcells
• foreign substances trapped by nodal reticular fibers

• 1. Skeletal Muscle Pump- skeletal muscle contractions
• 2. Respiratory Pump- respiratory movements
• 3. Lymph vessels have valves- prevent backflow

• return lymph back to blood stream
• 1. Left Thoracic Duct
• 2. Right Lymphatic Duct

• main duct returns lymph back to blood stream at left subclavian vein
• begin as dialation of cistema chyli

• receives lymph from the upper right side of the body
• empties lymph to internal jugular vein

• 1. Lymphocytes (Bcells, Tcells)
• 2. Macrophages
• 3. Reticular cells

• warriors
• made: red bone marrow
• mature: lymphatic system-(Bcells, Tcells)

• manage immune response
• some directly attack and destroy infected cells
• (lymphoid Tcell)

• protect by making plasma cells (daughter cells) that secrete antibodies into the blood
• (lymphoid Bcell)

mark antigens for destruction by phagocytes or other means

phagocyte foreign substances and help activate T cellls

dendric cells- capture antigens and bring them back to lymph nodes

• produce stroma (reticular fibers)
• network that supports the other cell types in lymphoid organs