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What is the formula to determine the maximum amount of blood allowed per animal per 2-3 weeks?
(wt in grams) x 0.01(1%)= (amount)mL
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What is the formula to convert temp from C to F?
(temp in C)x9/5+32= (temp in F)
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What is the formula to convert temp from F to C?
(temp in F -32)x5/9=(temp in C)
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What is the perferred temp for most lab rodents?
21 C
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What is the perferred ratio of light:dark for most lab animals?
12:12
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When do altricial rodents usually grow hair? Open eyes?
hair= 1 week; eye= 2 weeks
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What is the main function of brown fat tissue?
To store Glycogen
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Main component recovered by coprophagy is
B vitamin complex
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What does coprophagy mean?
Poop eating
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Taxonomically what does the term Rodentia refer to? (family, order, class, species, genus)
Order
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What is the minimum number of brother/sister mating necessary to be called an inbred strain?
20
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Strains and stocks; Which is inbred and which is outbred?
strains= inbred; stocks= outbred
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What organizationcertifies laboratory technicians and has researchers and technicians as members?
AALAS
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Teratology is the study of___
abnormal fetal development
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The 1985 amendment to the Animal Welfare Act provided excercise standards for what species?
Dog
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HEPA is a type of what?
Filter
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What is the term for an animal that is susceptible to certain diseases and placed in a room with other animals as a means of disease detection?
Sentinel
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What is the recommendation for ventilation rate for laboratory animals?
10-15/ hour
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Which organization's major focus is voluntary accreditation of laboratory animal facilities?
American Association for Accreditation of Laboratory Animal Care
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What is the best type of caging for a pregnant/ near pregnant rodent?
Shoebox
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What does IACUC stand for and who are 3 members?
Instatutional Animal Care and Use Committee; Veterinarian, scientist, and non-scientist
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What does AALAS stand for?
Association of Assistant Laboratory Animal Science
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Who wrote the guideline for euthanasia?
AVMA
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What are the 3 R's of research?
Reduce, Refine, and Replace
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What organization educates and certifies animal care technicians?
AALAS
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What are some jobs of IACUC?
inspect animal facilities and care programs, serve as information resourse for animal weolfare concerns, and review animal research proposals
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What book includes guiedlines for laboratory animals including rodents?
The guild fpr the care and use of laboratory animals
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T or F: The animal Welfare act is a law
True
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What are young mice called?
Pups
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What does the tem hypsodontic refer to?
Teeth that are constantally growing
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What defect do we expect in a nude mouse?
A poor immune system
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When moving a mouse or rat from one cage to another, what is the best method of restrain besides scruffing?
Grab and hold by the BASE of the tail
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What is the best way to determine sex in rodents?
compair the anogenital distance between several at a time
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What are the 3 phlebotomy site that can be used in rodents but NEVER while awake?
Cardiac, retro-orbital, or cranial vena cava
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What is the difference between a knockout and a transgenic?
A KO has an inactivated gene and a TG has an additional gene
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How does the USDA enforce and track the Animal Walfare Act?
Conduct Unannounced Inspections
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What is the term in the 3 R's for designing an experiment so that stress and pain to the animal is minimized?
Refinement
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Why are animals used to study humane disease?
The biomedical process in animal models can be very similar to humans
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What is the metric unit of measure for liquid?
Liter (L)
-
what are the 3 basic components of a cell?
membrane, nucleus, and cytoplasm
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What type of animal may have digrstive problems because of the lack of bacteria in the intestinal tract?
axenic
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What cause the reddish-brown staining of the fur on an albino rat?
porphoryin from the tears and saliva
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What is a good indication of a healthy newborn rodent?
a milk spot
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How often can a female mouse or rat go in to estrus?
Every 4-5 days
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What is postpartum estrus?
When a female goes back into estrus within 24 hours of parturition
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What technique is used to study in vivo vasculature in hamsters?
The cheek pouch is inverted and examined under a microscope
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How does the hamster stomach differ from the other rodents?
It is divided into 2 compartments
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What is the hamster flank organ also referred to as?
The scent gland
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How does hamster urine differ from that of rats and mice?
It is thick and milky
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What is unique about gerbil mating amoung rodents?
The generally mate with the same animal throughout life
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What type of activity pattern do gerbils exhibit?
Cyclic
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What is the ventral marking gland used for?
Marking territory
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What is done during hand mating of hamsters?
The female is removed after mating
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Why do gerils consume very little water?
They are adapted for life in the desert
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Why would a room a gerbils suddenly freeze after a loud noise?
They are trying not to be seen because they sense danger
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What color is the agouti mouse?
Brown with yellow bands
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When would you expect to see ringtail in rats?
When the room is too dry (humidity too low)
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Wet tail most commonly a disease of which rodent?
Hamster
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Genes, chromosomes, and DNA; What forms what that forms what?
DNA forms genes that form chromosomes
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What is the breeding scheme for producing animals with minimal variations?
Inbreeding
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What is the definition of conventional?
No special precautions are taken to prevent the introduction of disease into the colony
-
What species commonly requires a room temperature lower than most?
Rabbits
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What is the recommonded relative humidity for an animal room?
30-70%
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How would you know a room was under positive air pressure?
Air flows out into the hallway when the door is opened
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What is the descriptive term for guinea pigs and not other rodents at birth?
Precocious
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What is an essentail nutrient for Guinea pigs?
Vit C
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Guinea Pigs should NOT be breed after _____ old!
7 months
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What is a room called that is intended to separate incoming animals from the existing colony?
Quarantine
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The primary encloser refers to the animal's___.
Cage
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What is a gnotobotic animal?
An animal with defined flora
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What government agency in responsible for enforcing the Animal Welfare Act?
USDA
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Surgery rooms and rodent room are both held under what type of air pressure?
Positive
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What rodent is most common used for KO and TG?
Mouse
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Which rodents can be picked up by the base of the tail?
Rats and Mice
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What rodent has a cheek pouch?
Hamster
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What rodent is known to have seizures?
Gerbils
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What rodent does not have a postpatum estrus?
Hamster
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What rodent has a ventral marking gland?
Gerbil
-
What rodent has a flank gland?
Hamster
-
What rodent does not have a gallbladder?
Rat
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What rodent has a scientific name Rattus norvegicus?
Rat
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What rodent stomps when they think there is danger or during sexual activity?
Gerbil
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What rodent has babies that become haired and open eye by day 7?
Hamster
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What rodent is most susceptible to Tyzzer's Disease?
Gerbil
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What rodents may carry lymphocytic choriomenigitis?
Hamster
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What is the gestation period for a Guinea Pig?
60-65 days
-
What is the gestation period for the mouse?
19-21 days
-
What is the gestation period for the rabbit?
29-35 days
-
what is the gestation period for the rat?
21-23 days
-
What is the gestation period of a hamster?
15-18 days
-
What is the gestation period of the Gerbil?
24-26 days
-
Why is rabbit cageing pretreated with an acid solution prior to washing?
To remove urine scale left from minerials in rabbit urine
-
What are the terms for a male and female rabbit?
Buck and Doe
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What is Kindling?
Parturition in rabbits
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Which BSL level is most hazardous?
4
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Which type of cage wash equipment has a conveyor belt and operates like a car wash?
A tunnel washer
-
At what sound level is the use of hearing protection recommended
85 decibels
-
What is the proper minimum temperature for rinse water?
180 degrees
-
What is the definition of disinfection?
Reduction of the number of pathogenic microorganisms on an object to harmless levels
-
What is the minimum recommended time and temperature for autoclaving?
15 minutes at 250 degrees F
-
What is the definition od sterilization?
Destruction of all organisms on an object
-
What is the definition of sanitation?
Reduction of the number of microorganisms on an object to an acceptable public health standard
-
What type of injection is commonly used for tuberculin testing and allergy testing?
Intradermal
-
Which controlled substance is the most addictive?
schedule I
-
What does it mean if a diet is certified?
It does not contain comtaminants above a certain level
-
To which canine disease are ferrets susceptible?
Heartworm
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The armadillo is one of the few animal models of which human disease?
Leprosy
-
A zoonotic disease of sheep
Orf
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The crop of a bird is a part of what organ?
The esophagus
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Which is a common cause of gastric ulcers in ferrets?
Helicobacter mustelae
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