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Methanol poisoning
- sx: headache, nausea, vomiting, epigastric pain; vision loss and coma
- optic disc hyperemia
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Ethylene glycol poisoning
- anion gap metabolic acidosis, increased osmolar gap
- precipitates calcium oxalate crystals in the kidneys --> AKI
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Fluphenazine
- Typical antipsychotic
- injected every 2-3 weeks in schizophrenics
- Can cause hypothermia by inhibiting the body's shivering mechanism
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Neuroleptic malignant syndrome
- presentation: confusion, fever, muscle rigidity, daphoresis, elevated CK
- Tx: dantrolene (muscle relaxant), bromocriptine (dopamine agonist), amantadine (antiviral durg with dopaminergic properties)
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Torsades de pointes
- risks: h/o alcoholism, recent initiation of fluconazole, moxifloxacin
- Tx: stop all offending agents, administer magnesium sulfate
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TCA overdose
- hyperthermia
- anticholinergic effects: dilated pupils, intestinal ileus
- seizures
- prolong GRS
- Tx: sodium bicarbonate
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