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IgE mediated respiratory dz involving inflammation of the nasal mucosa membranes
Allergic Rhinitis
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What are the symptoms of Allergic Rhinitis (AR)?
- Congestion
- Rhinorrhea
- Itching
- Sneezing
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Newer classifications of AR are introduced based on what two symptom types
- Symptom frequency (intermittent or persistent)
- Symptom severity (mild/moderate/severe)
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Explain the stepwise management for intermittent symptoms.
- 1. Allergen avoidance
- 2. Mild: oral antihistamine, Intranasal antihistamine +/- decongestant or LTRA
- 3. Moderate/Severe: same as mild or intranasal steroid (or mast cell stabilizer) or allergen-specific immunotherapy
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Explain the stepwise management for Persistent symptoms.
- 1. Allergen avoidance
- 2. Mild:oral antihistamine, Intranasal antihistamine +/- decongestant or LTRA or intranasal steroid (or mast cell stabilizer) or allergen-specific immunotherapy
- 3. Moderate/Severe (in order): intranasal steroid, oral antihistamine, LTRA
- ADD for Rhinorrhea: ipratropium
- BLOCKAGE: oral decongestant or oral corticosteroid burst or allergen-specific immunotherapy
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MOA: competitive H1 antagonist, or an inverse agonist, of the early response
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