Cell Physiology & Structure

• author "me"
• tags ""
• description ""
• fileName "Cell Physiology & Structure"
• freezingBlueDBID -1.0
• Phospholipids in the cell membrane:
• Phosphatidylcholine
• Phosphatidylethanolamine
• Phosphatidylinositol (PI)
• Phosphatidylserine - negatively charged
• sphingomyelin

• Structural component of cell membrane
• PLA-arachidonic acid pathway
• Phospholipase C (PLC) pathway
• marking apoptotic cells for phagocytosis
• Self-antigens in autoimmune disorders

A lipid kinase that phosphorylates inositol phospholipids, derivatives of phosphatidylinositol, to transmit intracellular signals in response to growth factors and cytokines

Arachidonic acid cleaved from the two-position on membrane phospholipids by Phospholipase A to eventually form leukotrienes and prostaglandins