Pharm Classification

• MOA: Neutralize stomach acid
• Who gets: Peptic ulcer, gastritis, heartburn, hyperacidity
• Who doesn't: renal failure, electrolyte imbalance, & GI obstruction
• Mks us sad: diarrhea (Mg), constipation (Al, Ca), rebound hyperacidity (Ca)
• Names: Has -salt in it

• MOA: Reduce acid and cell responsiveness by blocking H2 receptor of parietal cells
• Who gets: GERD, PUD, Erosive esophagitis, hypersecretory conditions (Zollinger- Ellison syndrome)
• Who doesn't: Liver/ and kidney dysfunction
• Mks us sad: ALOC, hypotension, gynecomastia, gastro disturbances, impotence
• Names: -tidine

• MOA: bind to H-K pump to completely block acid secretion from parietal cells
• Who gets: erosive esophagitis (first line), GERD, ulcers, and hypersecretory conditions, H. pylori (with abx)
• Who doesn't: drug allergy
• Mks us sad: malig gastro tumors & osteoporosis (w/ long term use)
• Names: -prazole

• MOA: reduce incidence of gastric ulcers 
• Who gets: pts taking NSAIDs
• Who doesn't: Pregnant women (Category X)
• Mks us sad: abd cramps & diarrhea
• Names: Misoprostol (Cytotec)

• MOA: coat walls of GI tract and bind causative bacteria to wall for excretion thru stool. Has ASA in it
• Who gets: milder cases of diarrhea
• Who doesn't: children or teens recovering from flu or chickenpox.
• Mks us sad: Constipation, bleeding, blue gums
• Names: Bismuth subsalicylate (Pepto-Bismol), Activated Charcoal

• MOA: works to slow peristalsis by reducing contractions and smooth muscle tone of GI tract (SNS)
• Who gets it: Severe cases of diarrhea
• Who doesn't: narrow-angle glaucoma, GI obstruction, MG, paralytic ileus, preg cat C-X
• Mks us sad: urinary retention, impotence, hypotension, constipation, anxiety
• Names: Atropine, hyoscyamine

• MOA: works to slow peristalsis by reducing contractions and smooth muscle tone of GI tract (SNS)
• Who gets: severe diarrhea
• Who doesn't: alcohol intolerance, abd pain, peds, OB, lactation, hepatic dysfunction
• Mks us sad: constipation, abd px/ distention/ discomfort, N/V
• Names: codeine, diphenoxylate, loperamide

• MOA: suppress growth of diarrhea-causing bacteria & reestablish normal flora
• Who gets: uncomplicated severe diarrhea caused by abx therapy that destroys norm flora
• Who doesn't: no pathogens
• Mks us sad: constipation
• Names: Lactobacillus

• MOA: Absorb water into intestines, which increases bulk, promoting BM
• Who gets: acute & chronic constipation, IBS, diverticulosis
• Who doesn't: any abd problems (px, sx, N/V, impaction, GI obstruction)
• Mks us sad: impaction, F&E imbalance, gas formation, esophageal blockage, allergic reaction.
• Names: Citrucel, Metamucil

• MOA: directly lubricates stool and intestines
• Who gets: acute & chronic constipation, fecal impaction
• Who doesn't: any abd problems (px, sx, N/V, impaction, GI obstruction)
• Mks us sad: decreased absorption, F&E imbalance
• Names: Docusate salts (stool softner), mineral oil (lubricant laxative)

• MOA: Increasing fecal water content, which results in BM
• Who gets: chronic constipation, bowel prep
• Who doesn't: any abd problems (px, sx, N/V, impaction, GI obstruction)
• Mks us sad: abd bleeding, rectal irritation, electrolyte imbalance
• Names: Glycerin, Lactulose, GoLYTELY)

• MOA: increase osmotic pressure and draw water into the colon, producing a watery stool
• Who gets: Constipation, bowel prep
• Who doesn't: renal disease, abd pain, N/V, obstruction, rectal bleed
• Mks us sad: Mg toxicity, electrolyte imbalance, cramping, diarrhea, increased thirst
• Names: Mg hydroxide, mg sulfate, mg citrate

• MOA:induce intestinal peristalsis
• Who gets: acute constipation, bowel prep
• Who doesn't: any abd problems (px, sx, N/V, impaction, GI obstruction)
• Mks us sad: discolored urine, rectal irritation, gastric irritation, nutrient malabsorption, electrolyte imbalances
• Names: Senna, bisacodyl

• MOA: results from an antigen-antibody response similar to that after antigen exposure in natural disease process
• Use: prevent development of active disease in the event of exposure
• Type: Toxoid or vaccine

MOA: Production of one's own antibodies during actual infection

• MOA: Results from direct administration of exogenous antibodies
• Use: Provides temp protection against disease
• Type: Immunoglobulin or antitoxin

MOA:Transmission of antibodies from mother to infant through placenta or during breast-feeding