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How do motor proteins work?
Motor proteins use ATP as a source of energy for movement . Made up the head hinge and tail. the walking analogy the ground is the filament, your leg is the head and you hip is the hinge.
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Three types of motor protein movement
- 1.Motor protein carries cargo along the filament
- 2.Filaments move
- 3.Bending the filament
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What molecules make up the cell membrane /bilayer?
Lipids, Proteins and carbohydrates
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What are transmembrane proteins?
regions are physically embedded in bilayer. Across
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What are Lipid-ancored proteins?
Amino acid is covalently linked to a lipid
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What is a lipid raft?
lipids can also aggregate if they are strongly associated with one another, high amount of cholesterol, unique set.
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Factors affecting fluidity
- 1. Length of fatty acid tail- shorter tails are less likely to react creating more fluidity
- 2. Double Bonds- create a kink making it harder for the in interact
- 3.Cholerterol- can stabilize the membrane
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How are lipids synthesized?
- In eukaryotes, the _cytosol_ and _endomembrane system_ work together to synthesize lipids
- Fatty acid building blocks are made via
- enzymes in the cytosol or taken into cells from food
- Process occurs at cytosolic leaf of the _Smooth Endoplasmic Reticulum (ER)
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What is Passive Transport?
Requires no input of energy and goes down or with the gradient
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What is passive diffusion?
diffusion of a solute through a membrane with out a transport protein
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what is facilitated diffusion?
diffusion of a solute through a membrane with the help of a transport protein
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What is Active Transport?
Requires input of energy and goes up or against gradient
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what is isotonic?
Equal water and solute concentration on either side
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What is hypertonic?
Soulte concentration is higher and water concentration is lower
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What is Hypotonic?
The solute concentration is lower and the water concentration is higher.
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What is osmosis?
Water diffuses through the membrane from an area where there is more water to where there is less water
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What is crenation?
Shrinking of a cell- water goes out
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What is osmotic lysing?
Swelling and bursting of a cell- water goes in
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What are the two types of Transport Proteins?
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Describe a channel transport?
Forms an open passageway, for direct diffusion of ion or molecules
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Describe Transporters
Known as carriers, use conformational change like a pocket
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Name the three types of transporters
- 1. Uniporter
- 2.Cotransporter or Sympoter
- 3.Antiporter
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Describe a Uniporter
Transports a single ion or molecule
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Describe a Cotransporter/Symporter
Two or more ions transported in the same direction
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Describe a Antiporter
Two or more ions transported in the opposite direction.
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What is Endocytosis?
is a process for moving items that are outside of the cell into the cytoplasm of the cell.
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What is Exocytosis?
is a process for moving items from the cytoplasm of the cell to the outside.
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What is Endergonic?
not spontaneous, takes energy in and is positive free energy change
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What is Exergonic?
Is spontaneous, a release of energy and has a negative free energy charge
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What is catabolic?
Breaking down- Exergonic
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What is anabolic?
Synthesis of molecule- Endergonic
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What is Oxidation?
Removal of electron
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What is Reduction?
addition of an electron
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Describe the process of Proteasome
Breaks down proteins using Ubiquitin “tags” that target improperly folded proteins
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Describe Lysosomes break down
Contain hydrolyses to break down proteins, lipids, nucleic acids and carbohydrates
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What is metabolism?
Consists of a series of catabolic and anabolic process in order to reproduce.
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What is Competitive Inhibition?
Molecules bind to the active site inhibiting the ability for the substrate to bind
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What are non-competitive inhibitors?
Binds to allosteric site
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