-
Trazodone
helps pts sleep but not helpful for depression
-
black box warning
risk of suicide d/t lifting
-
3 major categories of antidepressants
-
TCAs
tricyclic antidepressants
-
first developed tcas
- imipramine
- first antidepressant used
-
TCAs do what
stimulate appetite
-
TCAs s/e
- anticholinergic
- no sense of euphoria
- not addicting
-
anticholinergic 6
- dry mouth
- visual disturbances
- constipation
- decr sweating
- urinary retention
- incr appetite
-
TCAs use cautiously in
- elderly
- start low and go slow w dosing
-
MAOIs
Monoamine oxidase inhibitors
-
MAOIs s/e 4
- anticholinergic
- cardiac
- risk of dependance
- risk of hypertensive crisis
-
cardiac probs with MAOIs 3
- tachy
- arrhythmias
- cardiotoxicity
-
foods to avoid w MAOIs
- high tyramine foods
- ages, fermented, pickled, smoked
- beer, salami, cheese
-
SSRIs
Selective serotonin reuptake inhibitors
-
SSRIs first developed
Prozac
-
SSRIs
3 advantages
- less s/e than others
- low potential for od
- safe for elderly (still low and slow)
-
SSRIs s/e 3
- anticholinergic (not as severe)
- decr sex drive
- cardiovascular effects
-
bipolar disorder 5
- mania w or w/o depression
- pts extremes of mood polarity;
- may feel euporic or depressed;
- may have rapid cycling at times
- crying one moment, euphoric the next
-
manic episode 5
- elevated, expansive, irritable mood
- begins suddenly
- escalates rapid
- last a wk to months
- followed by extreme depression
-
Bipolar I
hx of manic episode
-
manic episode
watch for...
safety
-
objective s/s
bipolar 3
- disturbed speech
- altered social, interpersonal relations
- altered act and appearance
-
subjective s/s
bipolar 2
- altered affect
- altered perceptions
-
antimanic/mood stabilizing medication
drug of choice
lithium carbonate
-
lithium carbonate
- bipolar
- takes 7-10 days to begin
-
lithium carbonate
watch
5
- sodium levels/diet
- incr na = decr lith level
- decr na = incr lith
- need balance
- maintain consistant na and h20 i&O
-
antimanic/mood
bipolar
meds
s/e 9
nausea, dry mouth, diarrhea, thirst, drowsiness, tremors (lithy shakes), wt gain, polyuria, polydipsia
-
monitor lithium levels closely
therapeutic level
0.6 - 1.2 mEg/L
-
monitor lithium levels
how and when
draw bld early in the am before first dose and 8-12 h after last dose
-
s/s lith tox 6
n/v/d, drowsy, musc wkness, lack coordination/ataxia, tinnitus, blurred vision
-
lithium cannot be used in
preg
-
nsg interventions for bipolar 6
- use matter of fact tone
- clear, concise directions & comments
- limit setting
- reinforce reality
- respond to legitimate complaints
- redirect pts to more healthy act
-
guns
- used more for suicide than homicide
- incr use by teens
-
-
suicide
precautions 4
- monitor for "sharps" (strings, cans)
- remove all means from reach (pills, guns)
- do not allow wkend passes
- freq observations
-
suicide
no harm agreement
contract w pt that they agree if they feel like harming themselves they come and talk to you first
-
benzodiazepines
- enhance effects of inhibitory neurotransmitter GABA;
- depresses cns
- GABA goes up and anx goes down
-
benzodiazepines
examples
- Klonopin
- ativan
- valium
- xanax
- librium for detox
-
desired actions of benzos
rprpp
- reduce anx
- promote sleep
- relax musc
- prevent seizures
- produce amnesia
-
antidote for benzos
flumazenil (Romazicon)
-
benzos s/e 2
- cns: drowsy, fat, decr coord
- PNS: occ constipation, double vision, hypotension, incont, urin retention
-
anx
nonspecific, unpleasant, feeling of discomfort w phisiologic and pschy sx that generally result from perception of threat to safety and security (subconscious)
-
fear
- id cause easily
- consciously recognize
-
maturational anx
- experiences that are expected as part of normal processes of g&d, for most ind in particular society
- start school, develop relations, new job
-
situational anx
less predictable, specific actions are taken only when the threat is eminent or after it occurs
-
situational anx
ex
ind recognize acute illnesses/accidents can occur - purchase health insurance but dont know exactly how or when it will happen
hurricanes and other natural disasters
-
mild anx
- +1
- constructive motivator, discuss source of anx, prob solve, accept anx as natural, benefit from it
-
psychomotor mild anx
energetic, fidgeting, muscle tension, good eye contact
-
emotional mild anx
slight irritability, feeling challenged, confident
-
cognitive mild anx
alertness, aware of surrounding, concentration, attentiveness
-
moderate anx
- +2
- destructive, decr anx-ventilation, crying, exercise, relax techs, refocus attention, relate feelings and behaviors to anx, then use prob-solving techs, give oral meds prn
-
modorate anx psychomotor
incr bp, pulse and resp, slight perspiration, startle reflex
-
emotional mod anx
motivated to decr anx, incr irritability, decr confidence
-
cognitive mod anx
difficulty concentrating, tangentiality, loose assocaition
-
severe anx
- +3
- decr anx, stimuli and pressure, use kind firm simple directions, use time out (seclusion), five im meds prn
-
severe anx emotional
extreme discomfort, feeling of dread, hypersensitivity
-
severe anx pscyhomotor
extreme musc tension, rapid pacing, reflex responses
-
severe anx cognitive
distorted perceptions, diff focusing, flight of ideas, disorientation
-
panic anx
- +4
- guide firmly, physically take control, give im meds, order restraints prn
-
panic anx psychomotor
actual flight or fight, suicide attempts, eyes fixed, incoherent
-
panic anx emotional
rage, depression, feeling totally drained
-
panic anx cognitive
word salad, clang associations, neologisms, disorganized perceptions
-
loss/threats related to anx
- health or ability to function
- self-esteem/respect
- self control
- control or power over own life
- status/prestige
- resources (emotional, physical, etc)
- loved ones
- freedom and needs and goals
-
descriptions of anx
- subjective experience detected only by obj behaviors
- emotional pain, apprehension, fearful, sense of powerlessness. warning sign, triggers behaviors, alerts for self defense, contagious, part of a process
-
freud id
pleasure principle, all abt me; unconscious drvie for self-perservation, reproduction, and group association; id is w/o a sense of right and wrong, and ruthlessly insists on immediate satisfaction of impulses and desires; babies are bundles of id
-
freud ego
promotes the ind/s satisfactory adjustment in relation to the environment; main funt is to establish an acceptable compromise bw the crude, pleasure seeking id and the inhibitions of the superego; mediator bw id and superego; helps relieve anx
-
freud superego
blindly rigid, strictly moralistic and as unrelenting and ruthless; inhibits id
-
conscience
punishes the ind thru feelings of guilt and anx when behavior deviated from strict standards
-
ego ideal
rewards the ind thru feelings of euphoria and well being
-
defense mechs
protect ego and relieve anx
-
selye general adaptation syndrome
GAS
- alarm
- resistance
- exhaustion
-
alarm
gas
any stressor that activates the prep for fight/flight; incr in alertness to mobilize resources; level of anx is mild +1, to moderate +2; learning and prob solving; when stressor cont and not resolved...moves to next stage
-
resistance
gas
ind strives to adapt to stress; coping and def mechs use increased; prob solving/learning difficult; moderate +2 to severe +3;
-
exhaustion
gas
stress that lasts too long; overwhelming; inability to cope; severe +3 to panic +4; defenses are exaggerated; personality disorganized; misperception; reduced orientation; violent, suicidal, immobilized; death w/o intervention
-
physiological responses to anx
sympathetic fight or flight
- dilated pupils
- incr resps, sweating, and hr
- any sx of fight or flight
-
coping w anx
- adaptive
- palliative
- maladaptive
- dysfunctiona;
-
adaptive
solves the prob that is causing anx, anx is decreased; pt is objective, rational, and productive; **most effective coping way
-
palliative
temp decr anx but does not solve prob; anx returns; temp relief allows pt to return to prob solving
-
maladaptive
unsuccessful attempts to decr anx w/o attempting to solve the prob; anx remains
-
dysfunctional
not successful in reducing anx or solving prob; functioning becomes difficult, new probs develop
-
nsg interventions r/t anx
- relieve anx**
- calm, quiet environment
- ask pts to id how they feel
- encourage to express feelings
- help pt id cause of feelings
- listen for pt expressions of helplessness
- plan and involve pts in act such as walks
-
anx
nonspecific unpleasant feeling of discomfort w physicologic and psychological sx that generally result from a perception of a threat to safety and security; anx is a sx
-
anx d/o
patterns of sxs and behaviors in which anx is either the primary disturbance or a secondary prob that is recognized w the prim sx are removed; has to disrupt adls more days than not over 6 mo
-
generalized anx d/o
ind experiences the sx of anx cognitively and physically; most common anx d/o, seen w depression, anx or worry is chronic and excessive, can be bt nothing at all; difficulty in controlling anx, habitual worrying way of coping to prevent something bad
-
phobic disorders
intense, irrational fear responses to an external object, act, or situation
-
social phobia
fear of being humiliated, scrutinized, or embarrassed in public
-
agoraphobia
fear of being in public or open spaces, places, or situations in which escape might be diff or help might not be available; may not leave home alone
-
specific phobia
fear of a specific object or situation that is not either 1 of the above; fear of animals, flying, or hts
-
obsessive compulsive disorder
disorder in which recurrent obsessions (thought) alternate w compulsions (behaviors). both are unwilled
-
hypochondriacs
worried abt having, or believe that they have, a serious dis based on the misinterpretation of bodily signs and sensations
-
dissociative identity disorder
existance of two or more identities or personalities that take control of the persons behavior; the host is unaware of the other personailities but the others might be aware of ea other to varying degrees
-
dissociative fugue
sudden, unexpected travel away from home or some other location w the assumption of a new identity or a confusion abt ones identity; travel and behavior appear norm; last from a few hrs to several days; rare and unusual follows severe psychosocial stress
-
dissociative amnesia
loss of mem or the inability to recall important personal info; usually occurs immediately after a traumatic event, one or more episodes of the inability to recall important personal info that is beyond ordinary forgetfulness
-
posttraumatic stress do
development of characteristics sxs (intense fear, helplessness, re-experiencing of events) following exposure to an extreme traumatic stressor; such as war, escaping fire, mva, that maybe a friend/fam member didnt escape
-
defense mechs
protect ego and relieve anx
-
denial
unconscious refusal to admit an unacceptable idea or behavior
-
repression
unconscious and invol forgetting of painful ideas
-
suppression
conscious exclusion from awareness anx-producing feelings, ideas, situations
-
rationalization
conscious or uncon attempts to make or prove that ones feelings or behaviors are justifiable
-
intellectualization
con or uncon, using only logical explanations w/o feelings or an affective component
-
dissociation
uncon seperation of painful feelings and emotions from an unacceptable idea, sit, or object
-
identification
con or uncon attempt to model one self after respected person
-
introjection
uncon incororating values and attitudes of others as if they were your own
-
compensation
con covering up for a wkness by overemphasizing or making up a desirable trait
-
sublimination
con or uncon channeling instinctual drives into acceptable activities
-
reaction formation
a con behavior that is exact opposite of an uncon feeling
-
undoing
con doing something to counteract or make up for a transgression of wrong doing
-
displacement
uncon d/c pent-up feelings to a less threatening object
-
projection
unco or con blaming someone else for ones difficulties or placing ones unethical desires on someone else
-
conversion
the uncon expression of intrapsychic conflict symbolically thru physical sx
-
regression
uncon return to a earlier and mroe comfy developmental level
-
major depression
anx accompanies depression
-
sx of depression
- affect change
- anhedonia
- irritability in kids and young adults
- fatigue
- apathy
- sleep disturbances
- wt changes
- psychomotor changes
- decr/lack of concentration
- inability to make decisions
- feelings of worthlessness/guilt
-
incr risk of suicide in
single white males <24 and >65
-
neurochemical cause of depression
decr levels of neurotransmitters, esp serotonin, norepinephrine, and in some cases dopamine
-
dexamethasone suppression test
give dexamethasone inj, if depression - urine and bld cortisol levels will not fall, 40% w severe dep fail to suppress any cortisol; not exclusive to the dx of dep
-
anhedonia
inability to experience pleasure
-
apathy
- no motivation/lack of feeling or interest
- indifferent
-
psychomotor changes
retardation or agitation
-
assessment tools for depression
- used to assess a pt for dep; baseline and cont:
- beck dep inventory
- hamilton rating scale for dep
- zung self rating dep scale
-
zung self rating depression scale
self rating assessment scale; pt w depress will score 50-69; highest possible 80
-
thorough h and p done to
rule out med or drug induced depre
-
nsg interventions for a depressed pt
- accept pt where they are and focus on strength
- reinforce decision making by pts
- respnd to anger therapeutically
- spend time w withdrawn pts
- make decisions for pts in acts for success
- assess for suicide - intent, plan, and means
-
antidepressant meds
do not mix, risk for serotonin syndrome
-
serotonin syndrome
overstimulation of serotonin at synapse, major s/s include hyperthermia, change in loc and musc rigidity
-
guide for dxing bipolar
young mania rating scale
-
-
antipsychotics
may be used alone or in conj w other meds
-
anticonvulsants
used as alternate for those that dont respnd to lith; valproates, gabapentin
-
sympathetic
fight or flight
- sweating
- incr bp - panic - shock = decr bld press
- incr cardiac op
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