1) All levels of allergic reactions and anaphylaxis in conjuction with Epinephrine
2) Extrapyramidal effects (dystonic reactions) are characterized by uncontrolled muscle twitching, lateral eye deviation, and feeling of a thick tongue, due to phenothiazine (Thorazine, Compazine, antipsychotics, narcotic potentiators and antiemetics) overdose
Diphenhydramine - Contraindications:
1) COPD including asthma
2) Pregnant or nursing mothers
Diphenhydramine - Precautions:
1) Hypotension
2) Enlarged prostate
3) Glaucoma
Diphenhydramine - Side effects:
1) Sedation resulting in drowsiness and lethargy
2) Dries bronchial secretions resulting in wheezing