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Diphenhydramine - Drug generic name:
Diphenhydramine
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Diphenhydramine - Drug trade name:
Benadryl
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Diphenhydramine - Class:
Antihistamine
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Diphenhydramine - Actions/pharmacodynamics:
- 1) Blocks histamine receptors
- 2) Has some sedative effects
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Diphenhydramine - Indications:
- 1) All levels of allergic reactions and anaphylaxis in conjuction with Epinephrine
- 2) Extrapyramidal effects (dystonic reactions) are characterized by uncontrolled muscle twitching, lateral eye deviation, and feeling of a thick tongue, due to phenothiazine (Thorazine, Compazine, antipsychotics, narcotic potentiators and antiemetics) overdose
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Diphenhydramine - Contraindications:
- 1) COPD including asthma
- 2) Pregnant or nursing mothers
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Diphenhydramine - Precautions:
- 1) Hypotension
- 2) Enlarged prostate
- 3) Glaucoma
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Diphenhydramine - Side effects:
- 1) Sedation resulting in drowsiness and lethargy
- 2) Dries bronchial secretions resulting in wheezing
- 3) Blurred vision
- 4) Headache
- 5) Palpitations
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Diphenhydramine - Adult dosage:
25-50mg
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Diphenhydramine - Route:
Slow IV push or deep IM
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Diphenhydramine - How supplied:
Ampule and prefilled syringe: 50mg/mL
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Diphenhydramine - Pediatric dosage:
1mg/kg up to 25mg
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