ClinMedV:Toxicology (Anticoag Rodenticides)

Rodenticides antagonize what that is important to coagulation ability?

vitamin K
What does blocking vitamin K ultimately inhibit?
- prothrombin factor II
- also factors VII XI and X
What should you try to do?

bring in package because tx differs from first to second generation of product
Although uncommon how else can pets get rodenticide toxicity?

ingestion of rats
Symptoms can sometimes be vague with rodenticide toxicity and may not present til

2-7 days after ingestion
The symptoms are related to bleeding and include:LVPPBMEDHHS
- lethargy
- v+
- pale mm
- petechia
- bruising
- melena
- epistaxis
- dypsnea
- hemothorax
- hematuria
- sudden death
dx is made based off of:HSBCPP
- hx
- symptoms
- blood work
- clotting test-prothrombin time(PT) and partial prostothrombin time(PTT)
tx includes:IAVCT
- induce voming
- activated charcoal
- vitamin K1 (best if oral)
- cathartic
- transfusion
How long should vitamin K tx continue?

3-4wks
What test is given before and after finishing meds?

PIVKA
The PIVKA tests for _ induced by vitamin K antagonism

proteins
The PIVKA looks for what accumulated in circulation?

inactive precursors
The PIVKA detects a deficiency in what clotting factors?
- II
- VII
- X
What is checked 2 days post ingestion and then 2 days after finishing vit K?

PT (prothrombin time)

Author

heather.dundas

238609

Card Set

ClinMedV:Toxicology (Anticoag Rodenticides)

Description

vti

Updated

2013-10-03T21:37:22Z

Show Answers