1. Image Upload 1
    Appositional growth in elastic cartilage
  2. Image Upload 2
  3. Image Upload 3
    Fibrocartillage, fibroblasts indicated by arrow, and isogenic group in high mag
  4. Image Upload 4
    Fibrocartilage.  C, chondrocyte; F, fibroblast.
  5. Image Upload 5
    Chondrocytes in fibrocartilage.  Wavy bundles of fibers are type I collagen.  Cartilage matrix (type II collagen) is immediately around the chondrocytes.   X700.
  6. Image Upload 6
    EM of fibrocartilage-3 chondrocytes in their lacunae. Note the abundance of rough endoplasmic reticulum. Chondrocytes synthesize the cartilage matrix. Fine collagen fibrils, sectioned in several places, are found around the chondrocytes and at the lower left side of the image. x3750.
  7. Image Upload 7
    Fibrocartilage—don’t see the fibroblasts, only the chondroblasts visible
  8. Image Upload 8s
    sharpey fibers
  9. Image Upload 9
    Chondrogenesis-Blastema formation from mesenchyme cells which will form a chondroblast
  10. Image Upload 10
    • Mesenchyme cells differentiate into chondroblasts which in turn give rise to chondrocytes.  Note the perichondrium surrounding the growing cartilage.
    • Future perochondrium surrounding the blastema
  11. Image Upload 11
    • Embryonic hyaline cartilage surrounded by the perichondrium.  Embryonic connective tissue (mesenchyme) is found outside the perichondrium.
    • Note absence of BVs in mesenchyme but there are other BVs in the other areas
  12. Image Upload 12
    growing cartilage surrounded by perichondrium
  13. Image Upload 13
    interstitial cartilage growth
  14. Image Upload 14
    • Example of the cartilage interstitial growth.  A. chondrocytes undergoing mitotic division. 
    • Note that immediately after division, daughter cells are found within the same lacuna (dashed line). 
    • B, later, daughter cells are separated from each other by the secretion of the extracellular matrix.
  15. Image Upload 15
    old chondrocytes and osteoarthritis
  16. Image Upload 16
    Trachea and esophagus. Note replacement of tracheal cartilage with bone
  17. Image Upload 17
    • Tracheal ring from elderly person. Darker
    • cartilage is normal matrix.  Lighter more
    • eosinophilic areas are bone tissue (B) which has replaced the original cartilage.  Marrow cavity has formed in the original cartilage structure.  Red star= marrow
    • cavity X 75
  18. Image Upload 18
    Trachea. Cartilage replacement by bone.  Asterisk = Bone marrow
  19. Image Upload 19
    • CC—cartilage canal, P—perichondrium
    • B: Cross section of CC
Card Set