What is the formula for corrected WBC count?
Observed count x 100/ 100 + nRBC count
Common causes of eosinophilia
Describe Howell- Jolly bodies
Dark blue inclusion inside RBC.
List the maturing cells in order to the maturation series of RBC's.
What is a reticulocyte?
Immature, anuclear RBC with some retained ribonuclear protein
How long does it take the bone marrow to respond to blood loss?
How does the bone marrow know it needs to respond?
The kidneys measure oxygen levels in the blood and release erythropoiten when levels are low enough which stimulates the bone marrow to begin erythropoiesis.
Three mechanisms in hemostasis
Stimulation of clotting cascade
List blood types in the canine
Which canine blood groups cause the most acute hemolytic reactions?
DEA 1.1 & 1.2
What group of canine blood types is the most prevalent?
List blood types in cats
Which cats are typially type B?
Which scenario results in the worst transfusion reaction?
Type B cats have very strong anti A alloantibodies and can have a fatal reaction if given type A blood.
Why do cats always have to be typed or crossmatched before any transfusion, but dogs do not?
Cats have alloantibodies so a severe reaction can occur the very first time the wrong blood is trasfused.
Name of the test used to blood type dogs. What does it detect?
Rapidvet-H; detects DEA 1.1
What is the name of the test used to blood type cats? What does it detect?
Rapidvet- H Agglutination test cards; A,B,AB also tests for auto agglutination.
Purpose of crossmatching? What does it detect?
Show serological compatibility between donor and recipient. Detects antibodies in plasma or serum against antigens on RBC's.
donor cells/ recipients plasma
donor plasma/ recipients cells
What are the two reactions examined in lab as evidence of an incompatible match?
Hemolysis & agglutination
Acute clinical signs of transfusion reactions?
Example of NI
Kittens with type A blood drink colostrum from a mother with type B blood.
List some blood parasites
What lab test could be done to ID blood parasites?
: IFA/ ELISA available
Snap 4DX/5DX; also test for HW antigen
Clin Path "Stubbie"