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Lesion Method
- study effects of tissue damage
- - clinical
- - experimental
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Recording Methods
- Electrical recording:
- - EEG (electroencephalograph), records fluctuations in electrical activity, useful for sleep and epilepsy research
- - evoked potential (or ERP), an EEG response evoked by a stimulus
- - single neuron recording, records action potentials from individual neurons: planted in nuclei of the same function
- Chemical recording:
- - microdialysis
- - sampling of cerebrospinal fluid (CSF)
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Drugs
- study how drugs, which cause neurochemical changes, affect behavior
- alter neurotransmitter by synthesis
- block storage of a transmitter
- stimulate of reduce release
- stimulate or block receptors
- block enzymatic breakdown or uptake of neurotransmitters
- - ex. dopamine antagonists (antipsychotics) treat schizophrenia
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Imaging methods
- CT or CAT (computerized tomography); brain structure
- sMRI (structure magnetic resonance imaging); brain structure (finer image than CT)
- fMRI (function magnetic resonance imaging); flow of oxygenated blood
- PET (positron emission tomography); e.g. glucose-related metabolic activity
- cerebral blood flow (xenon gas)
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