-
Name the typical antipsychotics
- haloperidol plus the -azines
- e.g. trifluoperazine, fluphenazine, thioridazine, chlorpromazine
-
Antipsychotics: MOA
block DA D2 receptors to increase cAMP
-
Name the atypical antipsychotics
Olanzaine, clozapine, quetiapine, risperidone, aripiprazole, ziprasidone
-
Lithium: tox
- tremor sedation edema heart block
- hypothyroidism
- polyuria (NDI)
- Ebstein's anomaly (atrialized right ventricle)
-
Buspirone: use and MOA
- GAD
- Stimulates 5-HT1A receptors
-
name the TCAs
- imipramine, desipramine, clomipramine
- amitriptyline, nortriptyline
- doxepin, amoxapine
-
TCAs: MOA
block NE and 5HT reuptake
-
TCAs: tox and tx
- Convulsions Coma Cardiotox
- treat with NaHCO3 for CV tox
-
SSRIs: name them
- fluoxetine
- paroxetine
- sertraline
- citalopram
-
SNRIs: name them
- venlafaxine (GAD)
- duloxetine (neuropathy, greater NE effect)
-
MAOis: name them
- phenelzine
- selegiline (B only)
- tranylcypromine
- isocarboxazid
-
Buproprion: MOA
increase NE and dopamine via unknown mechanism
-
Mirtazapine: MOA
- alpha2 antagonist increases NE and serotonin release
- 5HT2 and 3 receptor antagonist
- for depression
-
Maprotiline: MOA
- blocks NE reuptake
- for depression
-
Trazodone: MOA
- inhibits serotonin reuptake
- used for insomnia
- high doses needed for depression
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