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USMLE psych pharm
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Name the typical antipsychotics
haloperidol plus the -azines
e.g. trifluoperazine, fluphenazine, thioridazine, chlorpromazine
Antipsychotics: MOA
block DA D2 receptors to increase cAMP
Name the atypical antipsychotics
Olanzaine, clozapine, quetiapine, risperidone, aripiprazole, ziprasidone
Lithium: tox
tremor sedation edema heart block
hypothyroidism
polyuria (NDI)
Ebstein's anomaly (atrialized right ventricle)
Buspirone: use and MOA
GAD
Stimulates 5-HT1A receptors
name the TCAs
imipramine, desipramine, clomipramine
amitriptyline, nortriptyline
doxepin, amoxapine
TCAs: MOA
block NE and 5HT reuptake
TCAs: tox and tx
Convulsions Coma Cardiotox
treat with NaHCO3 for CV tox
SSRIs: name them
fluoxetine
paroxetine
sertraline
citalopram
SNRIs: name them
venlafaxine (GAD)
duloxetine (neuropathy, greater NE effect)
MAOis: name them
phenelzine
selegiline (B only)
tranylcypromine
isocarboxazid
Buproprion: MOA
increase NE and dopamine via unknown mechanism
Mirtazapine: MOA
alpha2 antagonist increases NE and serotonin release
5HT2 and 3 receptor antagonist
for depression
Maprotiline: MOA
blocks NE reuptake
for depression
Trazodone: MOA
inhibits serotonin reuptake
used for insomnia
high doses needed for depression
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Author
andresjm
ID
23679
Card Set
USMLE psych pharm
Description
USMLE psychiatry pharmacology
Updated
2010-06-15T20:08:58Z
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