Pharmacology Dr. Brown Ch 1 and 2

  1. Non-proprietary name means?
    Generic name, active ingredient 

    EX: Acetominophen
  2. Proprietary name means?
    Trade/Brand name

    EX: Tylenol
  3. Chemical name means?
    Organic structure
  4. Equivalent chemical formula, after years of patent coverage drug is being produced by other companies "Copy cats".
    Generic equivalent
  5. Powdered drugs pressed into disks or capsules
  6. Chewables mixed with flavoring
    Molded tablets 

    EX: Heartgard
  7. Drug forms formulated to be protected against stomach acid
    Enteric coated tablets
  8. Designed to release only small amounts of the drug as it moves through the GI tract
    Sustained release formulations
  9. Powdered drugs in a gelatin capsule
  10. Designed to be placed into the rectum where they are dissolved and release the drug to be absorbed across the membranes of the intestinal wall
  11. Drug completely dissolved in a liquid vehicle
  12. Drug particles suspended but not dissolved in the liquid vehicle
  13. Drug mixed with fat or oil
  14. Drug dissolved in sugar water
  15. Liquid dose form in an alcohol solution given orally
  16. Semisolid dose form that doesn't melt at body temperature

    EX: Dewormers in tubes
  17. Drug dissolved or suspended in an oil base applied to the skin by rubbing
  18. Drug dissolved in alcohol, meant for application on the skin

    EX: Tincture of Iodine
  19. Suspensions or solutions that liquefy at body temperature
  20. Drug suspension or solution that is meant to be dabbed or brushed onto the skin

    EX: Poison Ivy lotion
  21. Designed to prolong absorption of the drug from the site of administration
    Depot/ Repository Drug
  22. Repository solid dosage forms that is inserted under the skin that releases medication over an extended period (weeks to months)
  23. Therapeutic agent composed of specially prepared plant or animal parts rather than synthesized chemicals in a lab

    EX: Thyroid supplements, pancreatic enzyme powder
  24. Sources of information (5)
    • Package insert
    • Formularies 
    • Reference books
    • Compendium of Veterinary Products
    • Physicians desk reference
  25. Rx means
    Only by prescription
  26. USP stands for...
    Unites states Pharmocopeia
  27. Organization that sets the standards for manufacture of drugs sold in the US
  28. Reason or condition for which drug is to be used

    EX: For specific species, for specific disease, at a specific dose
  29. Any effect of the drug other than the intended effect
    Adverse/side effect
  30. Ingredient of the drug formulation that includes preservatives, stabilizers, and liquid media into which drug is dissolved or suspended
    Inert ingredients
  31. Glass containers opened by snapping off glass neck, dispose after one use

    EX: Vitamin K
  32. The amount of drug that is administered to a patient at one time
  33. General amount that any animal or patient should be given
  34. Extra label/Off-label use drugs
    Drugs used in a manner other than that listed on the drugs label

    EX: Different dose or route, different species, another purpose that intended, human approved drugs used with aniamls
  35. DEA
    Drug enforcement agency
  36. FDA
    Food and Drug administration
  37. USDA
    US department of agriculture
  38. EPA
    Environmental protection agency
  39. Responsibilities of veterinary professionals
    • Store medications safely
    • Calculate doses
    • Prepare, dispense and record medications used
  40. Who determines if a drug can be OTC or a prescription
  41. What must be on a prescription label
    • Name address, telephone number of the vet
    • Name of the client and clients address
    • Animal name
    • Drug name, concentration, number of units
    • Clear instructions for dosage, frequency, route of administration, and duration of treatment
    • Cautionary statements
    • Specified withdrawl or discard times
  42. What act passed in 1970 has to do with childproof containers
    Poison prevention packaging act of 1970
  43. Temperature ranges
    • Cold: not to exceed 46 degrees
    • Cool: 46-59 degrees
    • Room temperature: 59-86 degrees 
    • Warm: 86-104 degrees
    • Excessive heat: greater than 104 degrees
  44. Which act passed in 1970 has to do with controlled substances
    Comprehensive Drug abuse control act

    Regulates the possession of drugs that have the potential for physical addiction, psychological addiction and/or abuse
  45. C-I drugs
    Extreme potential for abuse and no medicinal purpose 

    EX: Heroin, LSD, crack cocaine
  46. C-II drugs
    High potential for abuse and may lead to severe physical or psychological dependence

    EX: Hydrocodone, Opium, Morphine
  47. C-III drugs
    Some potential for abuse, may lead to low or moderate physical dependence

    EX: Ketamine, Telazol
  48. C-IV drugs
    Low potential for abuse, may lead to limited physical dependence 

    EX: Diazepam, butorphanol
  49. C-V drugs
    Subject to state and local regulation, low potential for abuse
  50. Controlled drug log
    May be computer log or bound composition

    Date, owner and patients name, starting volume, amount used, ending volume, initials of person who used drug must be kept
  51. How long must a controlled substance log be kept?
    2 years
  52. Mean "cell poison"
    Cytotoxic drugs
  53. Chemotherapeutic agents (cytotoxic) drugs allow exposure though which means...
    • Skin from spillage
    • Inhalation of aerosolized drugs as the needle is withdrawn from a vial that has been pressurized 
    • Ingesting food contaminated with aerosol or direct contact
    • Inhalation from crushing/breaking tablets
    • Absorption or inhalation during opening of glass ampules
  54. How to safe handle cytotoxic drugs
    • Mix under ventilation hood
    • High efficiency filter mask
    • Specific gloves 
    • Long sleeved nonporous gown 
    • Goggles
    • Dispose of everything in biohazard
    • Proper precautions with urine/feces
    • Chemotherapy spill kit
  55. MSDS
    Material safety data sheet
  56. Manipulation to produce a dose form of a drug in any form other than what is approved by the FDA
  57. Examples of compounding drugs
    • Formulating drugs with flavor compounds
    • Formulating drugs into capsules
    • Formulating into a different dose form
    • Diluting commercially approved drugs
    • Mixing two or more drugs in a syringe
  58. Mass measured in what unit
  59. Volume measured in what unit
  60. Length measured in what unit
  61. To determine the dose you will need...
    • Weight of the animal (kg)
    • Dosage of the drug (mg/kg)
    • Concentration of the drug (mg/ml)
  62. TRUE OR FALSE. A precaution is a condition or situation in which a drug should not be given.
  63. TRUE OR FALSE. 10 mg/lb every 6 hrs for 3 days is and example of a dose and 250 mg is an example of a dosage.
    False, they are reversed
  64. TRUE OR FALSE. Extra-label drugs can be legally used by vets in animals intended for use as human food.
  65. TRUE OR FALSE. Suspensions must be shaken before administering; solutions do not.
  66. TRUE OR FALSE. Troches are commonly used with vet patients.
    False, lozenges are not ideal with animals
  67. TRUE OR FALSE. The R symbol indicates that the drug is restricted to use only by a vet.
    False, indicates a copyright
  68. TRUE OR FALSE. Adding acepromazine tranquilizer to ketamine is not considered compounding as long as its not sold to another practice.
    False, any mixing of 2 drugs is compounding
  69. TRUE OR FALSE. The use of pill vial caps that are not childproof is illegal in vet medicine because they violate the Poison Prevention Packaging Act of 1970.
    False, act doesn't apply to vets.
  70. Give 2 mg/kg every 8 hours for 10 days is an example of what
    Dosage regimen
  71. Vials are in which two forms?
    • Multidose
    • Single dose
  72. Most up to date drug information is usually found where?
    Package inserts
Card Set
Pharmacology Dr. Brown Ch 1 and 2
Chapters 1 and 2