Renal pyleo.txt

a bacterial infection in the kidney and renal pelvis; presence of active organisms in the kidney or the effects of kidney infections

results from repeated or continued upper UTI or the effects of such infections from reflux

with a urinary tract defect, obstruction, or most commonly when urine refluxes from the bladder back into the ureters

from urinary tract into the kidney tissue, bacteria triggers inflammatory response and local edema results

acute tissue inflammation, tubular cell necrosis and possible abscess formation anywhere in the kidney; fibrosis and scar tissue develop from the inflammation, the calices thicken and scars develop

microbes come in renal pelvis, inflammatory response, fibrosis (scar tissue), decreased tubular reabsorption and secretion and then impaired kidney function

Entry of bacteria during pregnancy, obstruction or reflux

If you had reflux as a child or spinal cord injury, bladder tmor, prostate enlargement or urinary tract stones

Lead to papillary necrosis and reflux

E coli; if blood borne, staph a and candida and salmonella

antibody reactions, cell-mediated immunity against the bacterial antigens or autoimmune reactions

women but after 65, men increases because of prostate issues

HTN, inability to conserve sodium, decreased urine concentrating ability resulting in nocturia, can develop hyperkalemia and acidosis

fever, chills, tachycardia, tachypnea, flank pain, tender costovertebral angle, ABD discomfort (colicky), nausea and vomiting, general malaise and fatigue, burning urgency or frequency of urination, nocturia, recent cystitis or treatment for UTI

Positive leukocyte esterase and nitrite dipstick and WBC and bacteria; clean catch method

manage pain (NSAIDS appropriately); usually broad spectrum antibiotics; 2 L of fluids unless contraindicated; surgical; BP control