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When did Wilhelm Conrad Roentgen discover x-rays?
November 8, 1895
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Who discovered radioactivity?
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Who discovered radium & polonium? When?
- Marie & Pierre Curie
- 7/1898 Po
- 12/1898 Ra
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Artificial radioactivity was discovered in ______ by __________
- 1934
- Irene Curie & Frederic Joliot
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Dose fractionating to achieve the same tumor response with less injury to normal tissue was discovered by
Henri Coutard & Claude Regaud
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The first therapeutic use of x-rays was on _________.
- January 28, 1896
- (breast cancer)
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What is the half-life of Cobalt-60
5.26 years
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The gross palpable extent and location of malignant growth:
Gross Tumor Volume (GTV)
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The tissue volume that contains the GTV and subclinical microscopic malignant disease:
Clinical Target Volume (CTV)
-
Contains the tumor and adjacent tissues:
- Planning Target Volume (PTV)
- (always larger than the GTV)
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The dose at a point that has been "forced" to 100%
Dose Nomalization
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What are the limitations of isodose curves?
(3)
- 1. Only depict the dose from a SINGLE BEAM
- 2. Represent dose distribution in ONE PLANE
- 3. Only for SQUARE or RECTANGULAR fields
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The region in which the dose gradually increases until it reaches a certain depth and then falls off due to the increasing thickness:
the Buildup Region
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What is the major factor in determining the depth (dmax) at which dose maximum occurs?
Beam energy
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When a photon beam encounters a surface obliquely, Dmax moves _________ to the surface.
Closer
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For electron beams, the Dmax and actual dose on the skin surface ________ with beam energy.
(increase or decrease)
Increase with beam energy
-
To calculate the energy needed to treat along 90% isodose line for electrons multiply the depth by ______.
-
To calculate the energy needed to treat along 80% isodose line for electrons multiply the depth by ______.
-
The angle separating the two central axes:
-
SSD + depth =
SAD Source to Axis Distance
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TFD or FFD
- Target to Film Distance
- or
- Film to Focal Distance
-
EPI
Electronic Portal Imaging
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What is the formula used to calculate the MU for electrons?
- %Pxd: percentage prescription dose
- e- cutout factor: 1
- ie: dose 200cGy/fx w/ 90%
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What is the formula used to calculate the wedge angle?
-
Rule of Thumb:
When in doubt when calculating energy to for an electron treatment the energy (MeV) should be ____ the maximum depth of the tumor.
The energy (MeV) should be 3X the maximum depth of the tumor.
ie: a 3cm depth = a 9MeV beam
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The energy of a photon beam divided by four will give you the depth of the beam's _______ in most cases.
-
What does the RT (T) stand for?
Registered Technologist in Radiation Therapy
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The first linear accelerator was developed by ____________ in ______.
Wilderoe in 1928
(to accelerate heavy ions)
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The purpose of this machine is to duplicate the geometry & mechanical movements of radiation therapy machine, what is it?
a Simulator
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What are the three primary methods of dose determination in a radiation therapy department?
- Ionization Chamber
- TLD's
- Photographic Film
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The ________ expresses the penetration and the quality or hardness of a beam.
Half Value Thickness (HVT)
-
The thickness of a material that reduces the intensity of the beam to half of its original value:
Half Value Thickness (HVT)
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What is the ratio of the absorbed dose at a given depth to the absorbed dose at a fixed reference point, usually Dmax ?
Percentage Depth Dose (PDD) or (%DD)
-
What is the ratio of the absorbed dose at a given depth in tissue to the dose at the same point when it is at Dmax ?
Tissue Maximum Ratio (TMR)
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The region near the edge of the field margin where the dose falls rapidly:
Penumbra
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The angle through which an isodose curve is tilted at the central axis of the beam at a specified depth.
-
What is the correction factor of the lung?
0.25
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When a tumor is not situated at mid-depth, it can be beneficial to deliver a higher dose from the field where the tumor is shallower by ________ the beams.
Weighting
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The wedge angle needed depends on the:
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What is the formula used to find the necessary gap size?
GAP:
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- if not otherwise specified, assume SSD is 100cm
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Define:
BSF
- Back Scatter Factor (BSF) The ratio of dose on the central axis at Dmax to the dose at the same point in air.
- *independent of SSD
- *depends on energy & field size
-
Dose rates _________ with field size.
(increase or decrease)
Increase
-
What is the ratio of the dose rate of a given field size to the dose rate of the reference field size?
Output Factor (OF)
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The intersection of the horizontal and vertical axes of rotation is referred to as the ___________.
Isocenter
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The _____ axis represents the patient's left-to-right direction.
X axis
+x indicates the patient's right - -x indicates the patient's left
-
The ______ axis represents the cephalad-to-caudal direction.
Y axis
- +y cephalad (cranial)
- -y caudal
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The _____ axis represents the anterior-to-posterior direction.
-
What is the name of a tissue equivalent material used to eliminate the skin sparing effect?
Bolus
Superflab most common type
-
Tissue-equivalent materials used in megavoltage radiation therapy to reduce the depth of the Dmax is called:
Bolus
eliminates the skin sparing effect
-
A sheet of Lucite placed in the beam to reduce it's depth of Dmax is called a ___________.
Beam Spoiler
-
What energy range does a conventional simulator operate in?
kV range
(photoelectric effect)
-
The dose delivered to a patient is dependent upon these six factors:
- 1. Depth of calculation point below the surface
- 2. Energy of the beam (penetrating power)
- 3. Density of tissue
- 4. SSD
- 5. Field Size (FS)
- 6. Collimator Design
SCEFDD: SSD, COLLIMATOR, ENERGY, FIELD SIZE, DEPTH, DENSITY
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What was the only measure of exposure for the early pioneers of xrt
The erythema dose
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The Manchester system of radium distribution was developed by:
Ralston Paterson & Herbert Parker
Manchester = Paterson & Parker
-
The pentrometer to measure the quality of x-rays was introduced by:
Benoist
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The Roentgen was internationally accepted as a unit of measure for x-rays and gamma rays in:
-
The rad as a unit of absorbed dose was recommended by the ICRU in:
-
The use of betatrons in XRT became unpopular because:
Betatrons produce low dose rates & have limited field sizes
-
Radiation therapy units operating at approx 50-120 kVp are:
Superficial units
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Insertion pf aluminum, copper & tin filter into the x-ray beam causes ________ to be absorbed
Low energy x-rays
-
Orthovoltage units usually operate at:
50-70 cm SSD
-
Orthovoltage units usually operate in the energy range of :
150-500 kVp
-
Orthovoltage beams are generally _______ penetrating than superficial beams
More
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LINACs were first developed:
following WWII
-
LINACs produce high energy beams by accelerating CHARGED particles in a ___________
Linear tube
-
Because electrons scatter readily in air ________ extending close to the patient's skin are used
Cones
-
A collimator _____ the beam.
Defines
-
The photon beam from a LINAC is intercepted by:
Ionization chambers & a flattening filter
-
A flattening filter reduces the __________ in the center of the unfiltered beam
Dose Rate
-
The first Co-60 machine was introduced in:
the 1950's
-
The average energy of a Cobalt 60 beam is:
1.2 MeV
-
The half-life of Cobalt 60 is:
5.26 years
-
The penumbra of a LINAC is ______ than that of a Cobalt 60 machine
Smaller
-
The point around which the source of the beam rotates
The isocenter
-
The secondary collimators are largely responsible for the _________ of the beam edges
Sharpness
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Simulators are primarily used to:
Duplicate the geometry of therapy machines
-
A HVT is a way of expressing the _______ of a beam.
QUALITY of a beam
-
Dose rates in air express:
Dose without a phantom & with a build-up cap at a given distance
-
Dose rates ________ with increased field size & ________ with increased distance.
- INCREASE w/ increased field size
- DECREASE w/ increased distance
-
Increasing the distance from 80 to 90 cm causes the dose rate to change by:
- 0.7901
- Use the Inverse Square Factor to solve:
-
Percentage depth dose is dependent on:
-
The TAR at 5 cm depth for a 10x10 field minus the TAR at 5 cm depth for a 0x0 field gives the:
Scatter Air Ratio (SAR)
-
The width of penumbra increases with:
Increased SSD & Source Size
Decreased Source-collimator distance
-
In a fixed SSD technique, the dose is usually normalized:
at Dmax
-
In an isocentric technique, the dose is usually normalized:
at the Isocenter
-
In a typical electron beam, only the ______ to ______ isodose lines bulge out in the penumbra region, causing great difficulties in matching adjacent electron fields uniformly
10% to 50%
-
Photon isodose curves used in dose calculations on a patient usually require corrections for:
Oblique incidence & surface irregularities
-
Electron isodose curves used in dose calculations on a patient usually require corrections for:
Beam obliquity & Surface irregularities
-
The depth of Dmax for any photon beam energy is reduced by:
- Larger field size &
- Oblique incidence
-
Treatment fields should always be shaped so that the beam edge:
Crosses perpendicular to the spinal cord
-
In port films of parallel opposed isocentric fields of a lung tumor, the _________ field will appear to include a longer segment of the spinal cord than in the _________ field.
-
To minimize the gap between two adjacent fields a ___________ can be used.
Half-beam block
-
When adjacent areas must be treated, it is best to calculate the _____ necessary between fields to prevent overlap.
-
When an isodose curve of about 22° is needed, isodose charts for an ______ and a _____ are used.
an Open field & a 45° wedge angle
-
In an electron beam, the _____ isodose curve bulges and the _____ isodose curve constricts.
20% bulges
90% constricts
-
When parallel opposed 6 mV photon beams are used in a 20 cm thick patient, the maximum dose will occur at:
The entrance & exit of each field
-
When a 4 mV and a 15 mV photon beam are used to treat parallel opposed fields in a 20 cm thick patient, the dose in the entrance/exit region is highest when the _____ beams are used.
4 mV
-
When a sector is skipped in an arc technique, the high dose area is shifted away from the __________.
skipped sector
-
When parallel opposed fields are used with the isocenter at mid-depth & one field is weighted twice as much as the other, the maximum dose is in the:
Entrance/exit region of the field with the HIGHER weight.
-
To minimize the risk of hot or cold spots in the junction between photon fields, the gap should be:
Moved several times during the course of treatment
-
Matching of electron beams on a chest wall is more difficult because some isodose curves _______ and others ______.
-
The angle of beam divergence is ________ farther from the central axis
Larger
-
When parallel opposed fields are used & the isocenter is at mid-depth in the chest, the length of the spinal cord is:
Longer in the anterior field than in the posterior
-
The three planes in a patient are across the body, along the body in a lateral view & along the body in an anterior view. Respectfully, these are referred to as:
Axial- across the body
Sagittal- along the body in a lateral view
Coronal-along the body in an anterior view
-
When a patient is re-aligned with a laser alignment system, it is necessary to align:
two points separated by distance
-
Treatment planning CT's are different diagnostic CT's because:
In a treatment planning CT the patient must be in the treatment position on a flat surface
-
The anterior & posterior skin surfaces seen on a lateral radiograph of a patient's pelvis does not represent the patient's:
skin surface in midline
-
Discrepancies in the patient/beam alignment between the first port film & the simulation film may be due to:
- Differences in laser alignment systems
- Different couch tops
- Differences in clothing under the patient
-
When the location of a contrast-filled bladder is transported from a set of orthogonal films to a transverse contour of the pelvis, the _______ film yields info in the right/left & cephalad/caudal directions while the ______ film yields info in the ant/post & cephalad/caudal directions
ANTERIOR: rt/lt sup/inf
LATERAL: ant/pos sup/inf
-
Uncertainties associated with delivering XRT can be totally avoided by:
No special means, as there is no way to do so
-
When the treatment fields are designed by the RadOnc, margins are always added around a tumor to account for:
- Uncertainties in determining tumor extent
- Penumbra
- Patient motion
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