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Bretylium
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Bretylium - Generic name:
Bretylium
Bretylium - Trade name:
Bretylium
Bretylium - Class:
Antiarrhythmic
Bretylium - Actions/pharmacodynamics:
1) Increases v-fib threshold
2) Blocks release of norepinephrine from peripheral sympathetic nerves
3) May convert v-fib to effective rhythm without defib; nickname is the "chemical defibrillator"
Bretylium - Indications:
1) V-fib refractory to Lidocaine
2) V-tach refractory to Lidocaine
3) PVCs refractory to first-line medication
4) Wide complex tachycardia refractory to Lidocaine and Procainamide
Bretylium - Contraindications:
None when used in management of life-threatening arrhythmias
Bretylium - Precautions:
1) Patients taking antihypertensive medications
2) May interact with sympathomimetics to potentiate their pressor effects
3) Do not use on symptomatic patients in v-tach. Proceed directly to cardioversion.
Bretylium - Side effects:
1) Hypotension, syncope, and bradycardia
2) Increased frequency of arrhythmias
3) Dizziness and vertigo
4) Nausea and violent vomiting
Bretylium - Adult dosage:
1) V-fib/v-tach
: 5 mg / kg initial bolus followed by 10 mg / kg every 15 minutes to a total of 30 mg / kg
2) Refractory v-tach with pulse
: 500 mg in 50 mL and infuse 10 mg / kg over 8 - 10 minutes
3) Drip
: 500 mg in 250 mL and infuse at 1 - 2 mg / minute
Bretylium - Route:
Rapid IV Push
Bretylium - How supplied:
Ampule: 500 mg / 10 mL
Bretylium - Pediatric dosage:
Safety in children has not been established
Author
texasaggie324
ID
23403
Card Set
Bretylium
Description
Bretylium details
Updated
2010-06-14T00:48:28Z
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