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Atropine - Generic name:
Atropine
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Atropine - Trade name:
Atropine
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Atropine - Class:
Parasympatholytic (anticholinergic)
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Atropine - Actions/pharmacodynamics:
- 1) Blocks acetylcholine receptors (decreases parasympathetic tone and thus increases heart rate)
- 2) Decreases gastrointestinal secretions
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Atropine - Indications:
- 1) Symptomatic bradycardia (PVCs, hypotension, or decreased LOC)
- 2) Asystole and symptomatic heart blocks
- 3) Organophosphate poisoning
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Atropine - Contraindications:
None when used in emergency situations
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Atropine - Precautions:
- 1) Total dose of 0.04 mg / kg OR 3 mg should not be exceeded except in cases of organophosphate poisonings
- 2) A-fib and a-flutter with rapid ventricular response
- 3) Glaucoma and COPD: hypertension can worsen
- 4) Use with caution in 2nd degree type II and 3rd degree heart block in AMI patients
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Atropine - Side effects:
- 1) Palpitations and tachycardia
- 2) Headache, dizziness, and anxiety
- 3) Dry mouth, papillary dilation, and blurred vision
- 4) Urinary retention (especially older males)
- 5) Overdose: blind, mad, hot, red, and dry
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Atropine - Adult dosage:
- 1) Bradycardia: 0.5-1.0 mg every 3-5 minutes to max
- 2) Asystole: 1 mg every 3-5 minutes to max
- 3) Organophosphate poisoning: 2-5 mg
- Minimum dose: 0.5 mg
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Atropine - Route:
IV, ET, or IM
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Atropine - How supplied:
Prefilled syringe: 1.0 mg / 10 mL
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Atropine - Pediatric dosage:
- Not indicated in newborns
- 1) Bradycardia: 0.01-0.03 mg / kg
- 2) Organophosphate poisoning: 0.05 mg / kg
- Minimum dose: 0.1 mg
- Maximum dose: 0.5 mg
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