Haloperidol (Haldol)

Haldol

Tranquilizer, Antipsychotic

Inhibits central nervous system (CNS) catecholamine receptors: strong antidopaminergic and weak anticholinergic. Acts on CNS to depress subcortical areas, mid-brain and ascending reticular activating system in the brain.

Acute psychotic episodes

Agitation secondary to shock or hypoxia. Hypersensitivity

Extrapyramidal signs and symptoms, restlessness, spasms, Parkinson-like symptoms, drooling, dystonia, hypotension, orthostatic, hypotension, nausea, vomiting, blurred vision.

Enhanced CNS depression and hypotension in combination with alcohol. Antagonized amphetamines and epinephrine. Other CNS depressants may potentiate effects.

5 mg/ml ampule.

• Adult: 2-5 mg IM every 30-60 minutes until sedation achieved.
• Pediactric: Not recommended.

• Onset: 10 minutes.
• Peak Effect: 30-45 minutes.
• Duration: variable (generally 12-24 hours).

Pregnancy safety: not established. Treat hypotension secondary to Haldol with fluids and norepinephrine, not epinephrine. Patient may also be taking Cogentin (benztropine mesylate) if on long-term therapy with Haldol.