Inhibits central nervous system (CNS) catecholamine receptors: strong antidopaminergic and weak anticholinergic. Acts on CNS to depress subcortical areas, mid-brain and ascending reticular activating system in the brain.
Acute psychotic episodes
Agitation secondary to shock or hypoxia. Hypersensitivity
Enhanced CNS depression and hypotension in combination with alcohol. Antagonized amphetamines and epinephrine. Other CNS depressants may potentiate effects.
5 mg/ml ampule.
Dosage and Administration
Adult: 2-5 mg IM every 30-60 minutes until sedation achieved.
Pediactric: Not recommended.
Duration of Action
Onset: 10 minutes.
Peak Effect: 30-45 minutes.
Duration: variable (generally 12-24 hours).
Pregnancy safety: not established. Treat hypotension secondary to Haldol with fluids and norepinephrine, not epinephrine. Patient may also be taking Cogentin (benztropine mesylate) if on long-term therapy with Haldol.