Adenosine

Adenosine

Adenosine

Antiarrhythmic

• 1) Slows AV conduction
• 2) 6 second half-life

PSVT

• 1) Second or third degree heart blocks
• 2) Sick sinus syndrome (ECG: wandering pacemaker)
• 3) Incompatible medications: Tegretol - epilepsy: Theophylline or other xanthines (coffee)

Arrhythmias, including blocks, are common during cardioversions

• 1) Facial flushing, headache, shortness of breath, dizziness, and nausea/vomiting
• 2) May cause transient asystole

"6, 12, and 12." 6 mg given via rapid IV push over 1-2 seconds followed by a rapid 20 mL saline bolus; if after 1-2 minutes no response, administer 12 mg via rapid IV push over 1-2 seconds followed by a rapid 20 mL saline bolus; if after 1-2 minutes no response, administer 12 mg via rapid IV push over 1-2 seconds followed by a rapid 20 mL saline bolus for a total dosage of 30mg. MAXIMUM: 30 mg.

• RIVP (Rapid IV Push)
• Administration should be through the shortest possible route (i.e. through a saline lock) at the most proximal site reasonably possible (i.e. at the antecubital site)

6 mg / 2 mL vials and prefilled syringes

• Weight less than 50 kg
• 1st dose: 0.05 - 0.10 mg / kg to max of 12 mg
• 2nd and subsequent doses: 0.10 - 0.15 mg / kg
• MAXIMUM: 0.3 mg / kg