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Function of Class 1B
- Accelerates depolarization
- only treats VT
-
Adverse effects of class 1B
- proarrythmic, HOTN, seizures (at toxic levels)
- dizzy, fatigue, RR drop
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Function of Class 1C
- Flecainide (Tambocor)
- *worst proarrythmic, delays VT reploarization, decrease conduction, contraction, increase HR
-
Adverse Effects of Class 1C
- *last resort drug
- high risk of mortality
-
Class 2 dysrhythmic adverse effects
- Propanolol
- bradycardia, bronchoconstriction, decrease BP, mask hypoglycemia
- *check CA levels
- *no COPD or HF pt
-
Function of Class 3
- Amiodarone
- delay repolarization, prolong QT
- *treat VT
-
Adverse Effects of Class 3
- category D in pregnancy, dizzy, tremors, insomnia
- **blindess due to sun exposure (photophobia)
- hepatitis, pulm toxicity
-
Class 4 Function
- Verapamil (Calan)
- slow AV conduction, depress SA contract, dilate coronaries
- Treat Afib/Aflutter
-
Adverse Effects of Class 4
- Verapamil (calan)
- constipation, nausea, bradycardia, heart block, HF, HOTN, ***peripheral edema
- **interacts with digoxin
-
Function of Adenosine
- decrease: automaticity, conduction at AV
- treat SVT
-
Adverse Effects of Adenosine
- ****IV Bolus only
- bradycardia, HOTN, red face, dyspnea, chest discomfort
- *keep on telemetry*
-
Function of Digoxin (Lanoxin)
- decrease: Av conduction, automaticity
- treat SVT only
-
Adverse Effects of Digoxin (Lanoxin)
- *risk of hypokalemia
- cardiotoxicity, n,v, abd pain, fatigue, vision changes
- ***green halo vision=dig poisoning!!!
-
Function of Class 1A
- Quinidine
- delay repolarization
- treats SVT and VT
-
Adverse Effects of Class 1A
- Quinidine
- *strong anticholinergic effects
- cardiotoxicty, arteriole embolism, HOTN with IV, cinchosism, **doubles dig
-
Other uses for Quinidine
Anti-malarial, Anti-pyretic
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