Quarter 4 GI pathology: Liver

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small areas of necrosis that develop and are widely scattered on the liver

Focal necrosis
Bacterial causes of focal necrosis
- typhoid fever
- streptococcal
hepatic necrosis that affects only cells of certain lobule

Zonal necrosis
Zonal necrosis that develops around the central vein caused by viral hepatitis and chronic venous congestion

Central zonal necrosis
zonal necrosis caused by yellow fever

mid zonal necrosis
Zonal necrosis caused by eclampsia

peripheral zonal necrosis
acute yellow atrophy of the liver, necrosis in all cells of most hepatic lobules

Massive (diffuse) necrosis
main cause of micro-nodular cirrhosis

Lennec's cirrhosis (nutritional)
Three main causes of Portal Cirrhosis
- Lennec's cirrhosis
- Post-hepatic cirrhosis
- Post-necrotic cirrhosis
two main causes of biliary cirrhosis
- primary or intra-hepatic biliary cirrhosis
- Secondary or extra-hepatic biliary cirrhosis
Budd-Chiari syncrome

Hepatic vein thrombosis (obstruction)
Causes of impaired intrahepatic blood flow
- Cirrhosis
- Sinusoid occlusion
- Systemic circulatory compromise
what percent of hepatoma are linked to HBV

90%
what types of hepatitis can cause hepatocellular carcinoma

B and C
expain the common channel theory of pancreatitis

gall stone blocks ampulla of Vater caused bile infection in pancreatic duct with activates trypsinogen to trypsin which digest the pancreas
Obstruction of pancreatic ducts theory

squamous metaplasia blocks ducts
what are two associated diseases of chronic pancreatitis
- deabetes mellitus
- steotorrhea
commonest site of pancreatic carcinoma

The head
metastasis of pancreatic carcinoma
- liver
- lungs
type of beta cell tumor

adenoma
pancreatic tumor that causes zollinger-ellison syndrome (increased production of gastric acid)

Alfa cell adenoma
associated symptoms of alfa cell adenoma
- recurrent peptic ulcer distal to first part of duodenum and jejunum
- long standing diarrhea

Author

bradley.knox

231826

Card Set

Quarter 4 GI pathology: Liver

Description

gi liver

Updated

2013-08-29T03:54:33Z