(1) Goal: create ex vivo system to predict liver metastases from colorectal cancer using biomatrices to promote personalized care
- (2) Purpose: limit severity of primary tumor metasis by predicting and
- pretreating the predicted sites of metastasis.
(3) Isolation and preservation of biomatrix scaffolds gently without destroying tissue-specific characteristics that best mimics human tissue.
Biomatrix scaffold - tissue extract enriched in extracellular components that has been completely decellularized; tissue-specific NOT species-specific. Preserves collagens, matrix components, and soluble signals (i.e., growth factors and cytokines).