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pharm endo 2/3
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description of drugs:
modification of somatostain
drugs:
Octreotide (Sandostatin)
Lanreotide (Somatuline Depot)
Vapreotide (Sanvar IR)
indication and kinetics for Octreotide?
acromegaly
carcinoid
VIPoma
IV, SC, IM
indication and kinetics for Lanreotide?
acromegaly
deep SC
indication and kinetics for Vapreotide:
esophageal varices
upper GI bleeding
variceal bleeding
IV
CI
caution c/ Type 1 diabetes
altered glucose metabolism
(hypoglycemia can result)
indication:
variceal bleeding
After pancreatic surgery (reduced suppression of pancreatic secretions)
severe refractory chemotherapy-induced diarrhea
hepatorenal syndrome
suppression of hormones or transmitters
what med is used for Severe refractory chemotherapy-induced diarrhea
Octreotide 100 mcg SC tid
SE:
Cardiovascular:·
Sinus bradycardia
GI related
: ·
Abdominal pain·
Diarrhea- resolves in 24 hrs
Nausea
CNS :·
Headache·
Fatigue
Author
merazar15
ID
230935
Card Set
pharm endo 2/3
Description
somatostatin analogs, growth hormone antagonist, ACTH
Updated
2013-08-22T20:15:58Z
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