pharm endo 2/3

description of drugs:

modification of somatostain
drugs:
- Octreotide (Sandostatin)
- Lanreotide (Somatuline Depot)
- Vapreotide (Sanvar IR)
indication and kinetics for Octreotide?
- acromegaly
- carcinoid
- VIPoma
- IV, SC, IM
indication and kinetics for Lanreotide?
- acromegaly
- deep SC
indication and kinetics for Vapreotide:
- esophageal varices
- upper GI bleeding
- variceal bleeding
- IV
CI
- caution c/ Type 1 diabetes
- altered glucose metabolism
- (hypoglycemia can result)
indication:
- variceal bleeding
- After pancreatic surgery (reduced suppression of pancreatic secretions)
- severe refractory chemotherapy-induced diarrhea
- hepatorenal syndrome
- suppression of hormones or transmitters
what med is used for Severe refractory chemotherapy-induced diarrhea

Octreotide 100 mcg SC tid
SE:
- Cardiovascular:·
- Sinus bradycardia
- GI related: ·
- Abdominal pain·
- Diarrhea- resolves in 24 hrs
- Nausea
- CNS :·
- Headache·
- Fatigue

Author

merazar15

230935

Card Set

pharm endo 2/3

Description

somatostatin analogs, growth hormone antagonist, ACTH

Updated

2013-08-22T20:15:58Z

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