erythropoietins

drugs:
- Epoetin
- Darepoetin
kinetics for
Epoetin alpha:
Darbepoetin alpha:
- Epoetin: elimination half-life is 4-8 hrs
- Darbepoetin: prolonged elim half-life; approx. 24 hrs, given IV or SC 1x q 4 wks
indication:

anemia
dosing titrate for chemotherapy- only initiate treatment if hemoglobin is:

<10 g/dL
what do you have to monitor when using erythropoietins?
Results of any dose adjustments made in response to this would not be seen for:
- Hematocrit!
- 2-6 wks
Do not increase the dose more frequently than:

once q 4 wks
SE:
- iron deficiency
- thrombosis
- HTN!!
- seizures
CI:

uncontrollable HTN
what is the target goal for hemoglobin?

≤11 g/dL

Author

merazar15

228618

Card Set

erythropoietins

Description

pharm

Updated

2013-07-30T18:34:16Z

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